HLA-DRB3

Description		major histocompatibility complex, class II, DR beta 3
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GO Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Late Endosome Membrane Trans-Golgi Network Membrane MHC Class II Protein Complex Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding MHC Class II Protein Complex Binding MHC Class II Receptor Activity Peptide Antigen Binding
	Biological Process	Adaptive Immune Response Immunoglobulin Production Involved In Immunoglobulin-mediated Immune Response Myeloid Dendritic Cell Antigen Processing And Presentation Peptide Antigen Assembly With MHC Class II Protein Complex Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Signal Transduction Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation
Pathways		Downstream TCR signaling Phosphorylation of CD3 and TCR zeta chains Translocation of ZAP-70 to Immunological synapse Generation of second messenger molecules MHC class II antigen presentation PD-1 signaling Interferon gamma signaling
Drugs		1D09C3 Coccidioides immitis spherule
Diseases
GWAS		Plantar warts ( 28928442)
Interacting Genes		4 interacting genes: CDCA8 CTAG1B MAP3K13 POMC
Entrez ID		3125
HPRD ID		09985
Ensembl ID
Uniprot IDs		A0A4D6G1L1 P79483
PDB IDs		2Q6W 3C5J 4H1L
Enriched GO Terms of Interacting Partners?
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