NIPBL

Description		NIPBL cohesin loading factor
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Integrator Complex SMC Loading Complex Intracellular Membrane-bounded Organelle Extracellular Exosome Scc2-Scc4 Cohesin Loading Complex
	Molecular Function	Chromatin Binding Protein Binding Protein C-terminus Binding Mediator Complex Binding Histone Deacetylase Binding Protein N-terminus Binding Chromo Shadow Domain Binding Promoter-specific Chromatin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Metanephros Development Heart Morphogenesis Outflow Tract Morphogenesis Cellular Response To DNA Damage Stimulus Mitotic Sister Chromatid Cohesion Brain Development Sensory Perception Of Sound Stem Cell Population Maintenance Positive Regulation Of Histone Deacetylation Establishment Of Mitotic Sister Chromatid Cohesion Maintenance Of Mitotic Sister Chromatid Cohesion Cellular Protein Localization Embryonic Forelimb Morphogenesis Forelimb Morphogenesis External Genitalia Morphogenesis Positive Regulation Of Multicellular Organism Growth Ear Morphogenesis Regulation Of Hair Cycle Fat Cell Differentiation Positive Regulation Of Ossification Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Embryonic Development Embryonic Digestive Tract Morphogenesis Digestive Tract Development Developmental Growth Eye Morphogenesis Regulation Of Developmental Growth Embryonic Viscerocranium Morphogenesis Cognition Face Morphogenesis Gall Bladder Development Uterus Morphogenesis Mitotic Cohesin Loading Establishment Of Protein Localization To Chromatin Cellular Response To X-ray Cohesin Loading Replication-born Double-strand Break Repair Via Sister Chromatid Exchange Positive Regulation Of Neuron Migration
Pathways		Cohesin Loading onto Chromatin
Drugs
Diseases
GWAS		Height ( 28552196 25282103 31562340) Malaria ( 31844061) Meat-related diet ( 32066663) Obesity-related traits ( 23251661) Weight ( 28552196)
Interacting Genes		8 interacting genes: CBX5 CDK6 DBN1 HINFP PRSS23 SP100 SUMO2 TRIO
Entrez ID		25836
HPRD ID		10560
Ensembl ID		ENSG00000164190
Uniprot IDs		A0A590UJS4 Q6KC79
PDB IDs		6WG3 6WGE
Enriched GO Terms of Interacting Partners?
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