PRDX5

Description		peroxiredoxin 5
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Peroxisome Peroxisomal Matrix Cytosol Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	RNA Polymerase III Transcription Regulatory Region Sequence-specific DNA Binding Peroxidase Activity Protein Binding Thioredoxin Peroxidase Activity Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	Apoptotic Process Inflammatory Response Response To Oxidative Stress Negative Regulation Of Transcription By RNA Polymerase III Cellular Response To Oxidative Stress Cellular Response To Reactive Oxygen Species Hydrogen Peroxide Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Redox Homeostasis Cellular Oxidant Detoxification
Pathways
Drugs		Auranofin Diminazene
Diseases
GWAS		Alopecia areata ( 20596022 25608926) Crohn's disease ( 28067908 21102463) Multiple sclerosis ( 31604244 24076602) Psoriasis ( 23143594) Psoriasis or type 2 diabetes (trans-disease meta-analysis) ( 33385400) Psoriasis vulgaris ( 26626624) Sarcoidosis ( 22837380) Vitiligo ( 27723757)
Interacting Genes		10 interacting genes: APP CCDC90B CDKN2D CLK1 ERBB2 ERBB3 ERBB4 NUFIP2 PEX5 SMCP
Entrez ID		25824
HPRD ID		05958
Ensembl ID		ENSG00000126432
Uniprot IDs		P30044
PDB IDs		1H4O 1HD2 1OC3 1URM 2VL2 2VL3 2VL9 3MNG 4K7I 4K7N 4K7O 4MMM
Enriched GO Terms of Interacting Partners?
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