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ALDH1A1

Description aldehyde dehydrogenase 1 family member A1
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
  • Axon
  • Synapse
  • Extracellular Exosome
Molecular Function
  • Retinal Dehydrogenase Activity
  • Aldehyde Dehydrogenase (NAD+) Activity
  • GTPase Activator Activity
  • Androgen Binding
  • Protein Binding
  • Benzaldehyde Dehydrogenase (NAD+) Activity
  • Aminobutyraldehyde Dehydrogenase Activity
  • NAD Binding
  • 3-deoxyglucosone Dehydrogenase Activity
Biological Process
  • Retinoid Metabolic Process
  • Cellular Aldehyde Metabolic Process
  • Gamma-aminobutyric Acid Biosynthetic Process
  • Fructosamine Catabolic Process
  • Maintenance Of Lens Transparency
  • Retinol Metabolic Process
  • Regulation Of Catalytic Activity
  • Cellular Detoxification Of Aldehyde
  • Negative Regulation Of Cold-induced Thermogenesis
Pathways
  • RA biosynthesis pathway
  • Fructose catabolism
  • Ethanol oxidation
Drugs
  • NADH
  • Vitamin A
  • Tretinoin
  • 1,4-Dithiothreitol
Diseases
GWAS
  • Alcohol consumption (drinkers vs non-drinkers) ( 31959922)
  • Refractive error ( 32231278)
  • Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
  • Sensorimotor dexterity ( 31596458)
Interacting Genes 5 interacting genes: ALDH2 BRCA1 NUPR1 POT1 PTPRF
Entrez ID 216
HPRD ID 00001
Ensembl ID ENSG00000165092
Uniprot IDs P00352 V9HW83
PDB IDs 4WB9 4WJ9 4WP7 4WPN 4X4L 5AC2 5L2M 5L2N 5L2O 5TEI 6DUM 7JWS 7JWT 7JWU 7JWV 7JWW
Enriched GO Terms of Interacting Partners?
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