USP18

Description		ubiquitin specific peptidase 18
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Deubiquitinase Protein Binding ISG15-specific Protease Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Regulation Of Inflammatory Response Negative Regulation Of Type I Interferon-mediated Signaling Pathway
Pathways		ISG15 antiviral mechanism Ub-specific processing proteases Regulation of IFNA signaling
Drugs
Diseases
GWAS		Systemic lupus erythematosus ( 33272962)
Interacting Genes		6 interacting genes: IFNAR2 ISG15 TMEM14A TRIM54 TWIST1 ZDHHC17
Entrez ID		11274
HPRD ID		06136
Ensembl ID		ENSG00000184979
Uniprot IDs		Q9UMW8
PDB IDs
Enriched GO Terms of Interacting Partners?
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