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Novel |
BNC1 |
basonuclin 1 |
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Novel |
CHRNA3 |
cholinergic receptor nicotinic alpha 3 subunit |
- Highly sodium permeable postsynaptic acetylcholine nicotinic receptors
- Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
- Highly calcium permeable nicotinic acetylcholine receptors
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- Nicotine
- Butabarbital
- Methadone
- Fluoxetine
- Dextromethorphan
- Levamisole
- Ethanol
- Amantadine
- Pentolinium
- Bupropion
- Levacetylmethadol
- Gantacurium
- Epibatidine
- Cytisine
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Novel |
COX7C |
cytochrome c oxidase subunit 7C |
- TP53 Regulates Metabolic Genes
- Respiratory electron transport
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- Cholic Acid
- N-Formylmethionine
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Novel |
CSK |
C-terminal Src kinase |
- GAB1 signalosome
- Phosphorylation of CD3 and TCR zeta chains
- Integrin signaling
- PD-1 signaling
- MAP2K and MAPK activation
- Signaling by moderate kinase activity BRAF mutants
- Signaling by high-kinase activity BRAF mutants
- Signaling by BRAF and RAF fusions
- Paradoxical activation of RAF signaling by kinase inactive BRAF
- Signaling downstream of RAS mutants
- Signaling by RAF1 mutants
- Negative regulation of FLT3
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- Dasatinib
- Staurosporine
- TG-100801
- Fostamatinib
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Novel |
CYP11A1 |
cytochrome P450 family 11 subfamily A member 1 |
- Pregnenolone biosynthesis
- Endogenous sterols
- Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)
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- 46,XY disorders of sex development (Disorders in androgen synthesis or action), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS)
- Congenital adrenal hyperplasia (CAH)
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Novel |
FAH |
fumarylacetoacetate hydrolase |
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- Fumaric Acid
- Acetoacetic acid
- 4-[Hydroxy-[Methyl-Phosphinoyl]]-3-Oxo-Butanoic Acid
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- Tyrosinemia; Tyrosinemia, type I; Tyrosinemia, type II; Tyrosinemia, type III; Hawkinsinuria
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Novel |
LINC00597 |
long intergenic non-protein coding RNA 597 |
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Novel |
MOV10L1 |
Mov10 like RISC complex RNA helicase 1 |
- PIWI-interacting RNA (piRNA) biogenesis
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Novel |
TNFRSF11A |
TNF receptor superfamily member 11a |
- TNFR2 non-canonical NF-kB pathway
- TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway
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- Paget's disease of bone and related disorders, including: ; Paget's disease of bone (PDB); Familial expansile osteolysis (FEO); Early-onset Paget's disease of bone (PDB2); Expansile skeletal hyperphosphatasia (ESH); Juvenile Paget's disease (JPD)
- Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
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Novel |
VCAM1 |
vascular cell adhesion molecule 1 |
- Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
- Integrin cell surface interactions
- Interleukin-4 and Interleukin-13 signaling
- Interferon gamma signaling
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- Ethanol
- Carvedilol
- Succinobucol
- Clove oil
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CDC42 |
cell division cycle 42 |
- GPVI-mediated activation cascade
- EGFR downregulation
- Rho GTPase cycle
- Regulation of actin dynamics for phagocytic cup formation
- Regulation of actin dynamics for phagocytic cup formation
- CD28 dependent Vav1 pathway
- EPHB-mediated forward signaling
- EPHB-mediated forward signaling
- DCC mediated attractive signaling
- Inactivation of CDC42 and RAC1
- VEGFA-VEGFR2 Pathway
- Myogenesis
- Myogenesis
- RHO GTPases activate KTN1
- RHO GTPases activate IQGAPs
- RHO GTPases activate PAKs
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate WASPs and WAVEs
- RHO GTPases Activate Formins
- RHO GTPases Activate Formins
- MAPK6/MAPK4 signaling
- Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
- G beta:gamma signalling through CDC42
- FCGR3A-mediated phagocytosis
- FCGR3A-mediated phagocytosis
- Factors involved in megakaryocyte development and platelet production
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- Aminophosphonic acid-guanylate ester
- Guanosine-5'-Diphosphate
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ETFB |
electron transfer flavoprotein subunit beta |
- Respiratory electron transport
- Protein methylation
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- Glutaric acidemia; Glutaric acidemia, type I (GA1); Glutaric acidemia, type II (GA2); Multiple acyl coenzyme A dehydrogenase deficiency
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FBXL17 |
F-box and leucine rich repeat protein 17 |
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HSPB2 |
heat shock protein family B (small) member 2 |
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PSEN1 |
presenilin 1 |
- Nuclear signaling by ERBB4
- Degradation of the extracellular matrix
- Regulated proteolysis of p75NTR
- NRIF signals cell death from the nucleus
- Activated NOTCH1 Transmits Signal to the Nucleus
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- NOTCH2 Activation and Transmission of Signal to the Nucleus
- EPH-ephrin mediated repulsion of cells
- Neutrophil degranulation
- NOTCH3 Activation and Transmission of Signal to the Nucleus
- NOTCH4 Activation and Transmission of Signal to the Nucleus
- Noncanonical activation of NOTCH3
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- Acne inversa; Hidradenitis supprativa
- Frontotemporal lobar degeneration (FTLD), including: Pick disease of brain; Frontotemporal dementia (FTD); Ubiquitin-positive frontotemporal dementia (UP-FTD); Progressive supranuclear palsy type 1 (PSNP1); Inclusion body myopathy with early-onset paget disease and frontotemporal dementia (IBMPFD); Frontotemporal dementia, chromosome 3-linked (FTD3)
- Alzheimer's disease (AD)
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