CNTRL - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	ENG	endoglin		Carotuximab	Hereditary hemorrhagic telangiectasia (HHT)
Novel	PBX3	PBX homeobox 3
Novel	SPTAN1	spectrin alpha, non-erythrocytic 1	Caspase-mediated cleavage of cytoskeletal proteins Nephrin family interactions NCAM signaling for neurite out-growth NCAM signaling for neurite out-growth Interaction between L1 and Ankyrins Interaction between L1 and Ankyrins RAF/MAP kinase cascade Neutrophil degranulation COPI-mediated anterograde transport		Early infantile epileptic encephalopathy; Ohtahara syndrome
Novel	TRAF1	TNF receptor associated factor 1	Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway
	MAP3K4	mitogen-activated protein kinase kinase kinase 4		Fostamatinib
	MAPK6	mitogen-activated protein kinase 6	MAPK6/MAPK4 signaling	Acetylsalicylic acid Minocycline
	TRADD	TNFRSF1A associated via death domain	Caspase activation via Death Receptors in the presence of ligand Regulation by c-FLIP RIPK1-mediated regulated necrosis CASP8 activity is inhibited TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway Regulation of necroptotic cell death Dimerization of procaspase-8 TNF signaling Defective RIPK1-mediated regulated necrosis

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