Search Results for: AP2M1

Novel Interactant Symbol Name
Associated Pathways
Binding Drugs
Associated Diseases
NAA11 N-alpha-acetyltransferase 11, NatA catalytic subunit
NCOR2 nuclear receptor corepressor 2
  • PPARA activates gene expression
  • NOTCH1 Intracellular Domain Regulates Transcription
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • Constitutive Signaling by NOTCH1 PEST Domain Mutants
  • Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
  • HDACs deacetylate histones
  • Notch-HLH transcription pathway
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • Nuclear Receptor transcription pathway
  • SUMOylation of transcription cofactors
  • Regulation of lipid metabolism by PPARalpha
  • Loss of MECP2 binding ability to the NCoR/SMRT complex
  • Regulation of MECP2 expression and activity
  • NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
  • HCMV Early Events
  • NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis
NDRG1 N-myc downstream regulated 1
  • TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain
  • Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
NKAPD1 NKAP domain containing 1
PRPF18 pre-mRNA processing factor 18
PRPF38A pre-mRNA processing factor 38A
  • mRNA Splicing - Major Pathway
PRR13 proline rich 13
PTS 6-pyruvoyltetrahydropterin synthase
  • Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
  • Mycophenolate mofetil
  • Biopterin
  • Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
RALBP1 ralA binding protein 1
  • Rho GTPase cycle
RNF111 ring finger protein 111
  • Downregulation of SMAD2/3:SMAD4 transcriptional activity
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
  • Formation of Incision Complex in GG-NER
  • Antigen processing: Ubiquitination & Proteasome degradation
RPL22 ribosomal protein L22
  • L13a-mediated translational silencing of Ceruloplasmin expression
  • Peptide chain elongation
  • SRP-dependent cotranslational protein targeting to membrane
  • SRP-dependent cotranslational protein targeting to membrane
  • Viral mRNA Translation
  • Selenocysteine synthesis
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Formation of a pool of free 40S subunits
  • GTP hydrolysis and joining of the 60S ribosomal subunit
  • Eukaryotic Translation Termination
  • Regulation of expression of SLITs and ROBOs
  • Response of EIF2AK4 (GCN2) to amino acid deficiency
  • Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
RPL38 ribosomal protein L38
  • L13a-mediated translational silencing of Ceruloplasmin expression
  • Peptide chain elongation
  • SRP-dependent cotranslational protein targeting to membrane
  • SRP-dependent cotranslational protein targeting to membrane
  • Viral mRNA Translation
  • Selenocysteine synthesis
  • Major pathway of rRNA processing in the nucleolus and cytosol
  • Formation of a pool of free 40S subunits
  • GTP hydrolysis and joining of the 60S ribosomal subunit
  • Eukaryotic Translation Termination
  • Regulation of expression of SLITs and ROBOs
  • Response of EIF2AK4 (GCN2) to amino acid deficiency
  • Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
RRP12 ribosomal RNA processing 12 homolog
RSPH14 radial spoke head 14 homolog
RUNDC3A RUN domain containing 3A
SFRP4 secreted frizzled related protein 4
  • Cyclothiazide
  • Perindopril
STON2 stonin 2
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
SYNJ1 synaptojanin 1
  • Synthesis of PIPs at the plasma membrane
  • Synthesis of IP2, IP, and Ins in the cytosol
  • Synthesis of IP3 and IP4 in the cytosol
  • Clathrin-mediated endocytosis
TASOR transcription activation suppressor
TBC1D5 TBC1 domain family member 5

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