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AP2M1 and PRPF18
Data Source:
BioGRID
(two hybrid)
AP2M1
PRPF18
Description
adaptor related protein complex 2 subunit mu 1
pre-mRNA processing factor 18
Image
GO Annotations
Cellular Component
Lysosomal Membrane
Cytosol
Plasma Membrane
Clathrin-coated Pit
AP-2 Adaptor Complex
Endocytic Vesicle Membrane
Clathrin-coated Endocytic Vesicle Membrane
Cytoplasmic Vesicle
Endolysosome Membrane
Intracellular Membrane-bounded Organelle
Clathrin-coated Endocytic Vesicle
Extracellular Exosome
Nucleus
Spliceosomal Complex
U5 SnRNP
Nuclear Speck
U4/U6 X U5 Tri-snRNP Complex
U2-type Post-spliceosomal Complex
Molecular Function
Signal Sequence Binding
Protein Binding
Lipid Binding
Clathrin Adaptor Activity
Ion Channel Binding
Low-density Lipoprotein Particle Receptor Binding
Protein Binding
Biological Process
Intracellular Protein Transport
Endocytosis
Vesicle Budding From Membrane
Vesicle-mediated Transport
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Receptor Internalization
Low-density Lipoprotein Particle Receptor Catabolic Process
Low-density Lipoprotein Particle Clearance
Cellular Protein-containing Complex Assembly
Ephrin Receptor Signaling Pathway
Regulation Of Defense Response To Virus By Virus
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Membrane Organization
Clathrin-dependent Endocytosis
Regulation Of Vesicle Size
Negative Regulation Of Protein Localization To Plasma Membrane
Generation Of Catalytic Spliceosome For Second Transesterification Step
MRNA Processing
RNA Splicing
Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription
Pathways
Nef mediated downregulation of CD28 cell surface expression
Nef Mediated CD4 Down-regulation
Retrograde neurotrophin signalling
Retrograde neurotrophin signalling
Nef Mediated CD8 Down-regulation
Gap junction degradation
Formation of annular gap junctions
MHC class II antigen presentation
EPH-ephrin mediated repulsion of cells
Recycling pathway of L1
Recycling pathway of L1
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
VLDLR internalisation and degradation
LDL clearance
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Major depressive disorder (
22472876
)
Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU) (
24025145
)
Craniofacial microsomia (
26853712
)
Lupus nephritis in systemic lupus erythematosus (
24925725
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Skin pigmentation (
28300201
)
Interacting Genes
76 interacting genes:
ADRA1B
AGTR1
AP2B1
AQP4
ARRB2
ATXN1L
BDKRB2
C1orf35
CACNA1A
CD22
CD3D
CDK11B
CORO7
CSNK2B
CTLA4
CXorf51A
CXorf51B
DAB2
DCX
DPPA2
DVL2
EAF1
EHD2
EIF1AD
FAM90A1
FURIN
FXR2
GAK
GRIN2B
H2BC10
H2BC13
H2BC21
H2BC4
H2BC6
H2BC7
H2BC8
HEXIM2
HTR6
IKZF1
KCNJ11
KNOP1
LAMP1
LTB4R2
LY9
MAB21L3
MED4
MEGF10
MFAP1
MPP1
MTURN
NAA11
NCOR2
NDRG1
NKAPD1
PRPF18
PRPF38A
PRR13
PTS
RALBP1
RNF111
RPL22
RPL38
RRP12
RSPH14
RUNDC3A
SFRP4
STON2
SYNJ1
TASOR
TBC1D5
TGOLN2
TMA16
UBC
UTP25
ZBTB8A
ZNF581
81 interacting genes:
AGTRAP
AMOTL2
AP2M1
ASCC2
BEGAIN
BICD2
BLZF1
CADPS
CALCOCO2
CARD10
CARD9
CBY2
CCDC102B
CCDC136
CCDC150
CCDC57
CCNC
CDR2
CEP70
CSRNP1
DVL3
EFHC2
EVI5L
FERMT3
FSD2
GAS8
GCC1
GOLGA2
GOLGA6L9
GPBP1
GRIPAP1
HMBOX1
HOMEZ
HOOK2
HSF2BP
IKBKG
IKZF1
KANK2
KCTD7
KIFC3
KRT31
KRT34
KRT35
KRT39
KRT40
LDOC1
LZTS1
LZTS2
MCC
MDFI
MEOX2
MTUS2
NACC1
NECAB2
NINL
NUTM1
NUTM2F
OSBPL3
PDE9A
PFDN5
PIBF1
PICK1
PLEKHG4
PNMA1
PPIH
PRKAR1B
RHOU
RINT1
SCHIP1
SPRED1
STX11
TRAF2
TRIM23
TRIM27
TRIM54
TSNAX
TSNAXIP1
UBXN11
ZNF526
ZNF639
ZRANB1
Entrez ID
1173
8559
HPRD ID
03014
05407
Ensembl ID
ENSG00000161203
ENSG00000165630
Uniprot IDs
B4DNB9
E9PFW3
Q96CW1
Q99633
PDB IDs
1H6E
6BNT
6URI
2DK4
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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