NEU1 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
GLB1	galactosidase beta 1	Glycosphingolipid metabolism Keratan sulfate degradation HS-GAG degradation MPS IV - Morquio syndrome B Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation	Lactose	Galactosialidosis GM1 gangliosidosis Mucopolysaccharidosis type IV (MPS4), including: Morquio syndrome A (MPS4A); Morquio syndrome B (MPS4B)
GOLM1	golgi membrane protein 1	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
GPR152	G protein-coupled receptor 152
GPX8	glutathione peroxidase 8 (putative)	Detoxification of Reactive Oxygen Species	Glutathione Glutathione disulfide
HSD17B11	hydroxysteroid 17-beta dehydrogenase 11	Estrogen biosynthesis	Aetiocholanolone
JUNB	JunB proto-oncogene, AP-1 transcription factor subunit	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Interleukin-4 and Interleukin-13 signaling NGF-stimulated transcription NGF-stimulated transcription
KCNA2	potassium voltage-gated channel subfamily A member 2	Voltage gated Potassium channels	Enflurane Promethazine Miconazole Dalfampridine
KCNA4	potassium voltage-gated channel subfamily A member 4	Voltage gated Potassium channels	Enflurane Promethazine Miconazole Arginineamide Dalfampridine
LIG4	DNA ligase 4	2-LTR circle formation Nonhomologous End-Joining (NHEJ)		DNA repair defects, including the following six diseases: Ataxia telangiectasia (AT); Ataxia-talangiectasia-like syndrome; Nijmegen syndrome; DNA ligase I deficiency; DNA ligase IV deficiency; Bloom's syndrome
LMNA	lamin A/C	XBP1(S) activates chaperone genes Signaling by BRAF and RAF fusions		Restrictive dermopathy Emery-Dreifuss muscular dystrophy Dilated cardiomyopathy (DCM) Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy Mandibuloacral dysplasia Congenital muscular dystrophies (CMD/MDC), including: Merosin-deficient CMD (MDC1A); Ullrich CMD (UCMD); Integrin alpha7-deficient CMD; CMD with joint hyperlaxity (CMDH); CMD with epidermolysis bullosa; Walker-Warburg syndrome (WWS); Muscle-eye-brain disease (MEB); Fukuyama CMD (FCMD); CMD with muscle hypertrophy (MDC1C); CMD with severe intellectual impairment and abnormal glycosylation (MDC1D); Rigid spine syndrome (RSS); LMNA-deficient CMD; CMD with respiratory failure and muscle hypertrophy (MDC1B); Bethlem myopathy Limb-girdle muscular dystrophy (LGMD) Familial partial lipodystrophy (FPL), including the following four diseases: Kobberling-type lipodystrophy (FPLD1); Dunnigan-type lipodystrophy (FPLD2); Dunnigan-like lipodystrophy (FPLD3); AKT2 associated lipodystrophy Hutchinson-Gilford progeria syndrome
MGST3	microsomal glutathione S-transferase 3	Glutathione conjugation Aflatoxin activation and detoxification	Glutathione
MUC1	mucin 1, cell surface associated	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family Interleukin-4 and Interleukin-13 signaling O-linked glycosylation of mucins Termination of O-glycan biosynthesis	TG4010
SLC10A1	solute carrier family 10 member 1	Recycling of bile acids and salts
SLC10A6	solute carrier family 10 member 6	Transport of bile salts and organic acids, metal ions and amine compounds
SLC18A1	solute carrier family 18 member A1	Na+/Cl- dependent neurotransmitter transporters	Reserpine Norepinephrine Ephedra sinica root MMDA Metamfetamine
SLC39A9	solute carrier family 39 member 9
TMEM14B	transmembrane protein 14B

Search Results for: NEU1