NEU1 and SLC39A9

Data Source:
BioGRID (two hybrid)

		NEU1	SLC39A9
Description		neuraminidase 1	solute carrier family 39 member 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Lysosome Lysosomal Membrane Plasma Membrane Membrane Cell Junction Specific Granule Lumen Lysosomal Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome	Integral Component Of Membrane
	Molecular Function	Exo-alpha-sialidase Activity Protein Binding Alpha-sialidase Activity Exo-alpha-(2->3)-sialidase Activity Exo-alpha-(2->6)-sialidase Activity Exo-alpha-(2->8)-sialidase Activity	Protein Binding Metal Ion Transmembrane Transporter Activity
	Biological Process	Glycosphingolipid Metabolic Process Ganglioside Catabolic Process Oligosaccharide Catabolic Process Neutrophil Degranulation	Zinc Ion Transport Transmembrane Transport
Pathways		Glycosphingolipid metabolism Sialic acid metabolism Defective NEU1 causes sialidosis Neutrophil degranulation
Drugs		Oseltamivir
Diseases		Sialidosis; Mucolipidosis I Galactosialidosis Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Basal cell carcinoma ( 27539887) Blood protein levels ( 28240269) Estimated glomerular filtration rate ( 31152163) Inflammatory bowel disease ( 28067908) Neutrophil percentage of white cells ( 32888494) Platelet distribution width ( 32888494) Small cell lung carcinoma ( 28604730) Squamous cell lung carcinoma ( 28604730) Ulcerative colitis ( 28067908)	Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		29 interacting genes: AQP6 CCR9 CD79A CERS3 CERS4 CREB3 CREB3L1 CTSA EBP EEF1A1 ERGIC3 ERRFI1 GLB1 GOLM1 GPR152 GPX8 HSD17B11 JUNB KCNA2 KCNA4 LIG4 LMNA MGST3 MUC1 SLC10A1 SLC10A6 SLC18A1 SLC39A9 TMEM14B	40 interacting genes: ANKRD46 APH1A AQP6 BNIP2 CBARP CD79A CERS3 CPLX4 CRB3 CREB3L1 CREB3L3 CYB5B ELOVL5 EVI2B FCER1G FFAR2 GJA8 GPR101 HERPUD2 HTR2C LNPEP MANBAL MFSD14B MFSD5 MGST3 NEU1 RTP2 SERINC2 SLC10A6 SLC16A2 SLC39A2 SLC66A1 SLC7A1 SSMEM1 TM4SF18 TMEM140 TMEM237 TMEM86B TRHR VMP1
Entrez ID		4758	55334
HPRD ID		09751	15387
Ensembl ID		ENSG00000204386	ENSG00000029364
Uniprot IDs		Q5JQI0 Q99519	B4DDK0 C4N9M8 M0QX28 Q9NUM3
PDB IDs
Enriched GO Terms of Interacting Partners?
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