NUP153 and NUTF2

Data Source:
BioGRID (pull down)

		NUP153	NUTF2
Description		nucleoporin 153	nuclear transport factor 2
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GO Annotations	Cellular Component	Nuclear Pore Nucleoplasm Nucleolus Cytosol Membrane Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Host Cell Nuclear Pore Nuclear Basket	Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytosol Nuclear Membrane Nuclear Pore Central Transport Channel Extracellular Exosome
	Molecular Function	DNA Binding Protein Binding Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein-membrane Adaptor Activity Metal Ion Binding	Protein Binding Structural Constituent Of Nuclear Pore Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Regulation Of Glycolytic Process RNA Export From Nucleus MRNA Export From Nucleus TRNA Export From Nucleus Protein Import Into Nucleus Viral Process Protein Sumoylation Viral Transcription Viral Entry Into Host Cell Negative Regulation Of RNA Export From Nucleus Nuclear Pore Complex Assembly Regulation Of Gene Silencing By MiRNA Viral Penetration Into Host Nucleus Intracellular Transport Of Virus Regulation Of Cellular Response To Heat	Protein Import Into Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Positive Regulation Of Protein Import Into Nucleus MRNA Transport Protein Localization To Nuclear Pore Negative Regulation Of Vascular Endothelial Growth Factor Production
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events
Drugs
Diseases
GWAS		Height ( 18391951) Obesity-related traits ( 23251661)	Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		27 interacting genes: APC BRCA1 CLK1 DYNLT1 IPO5 KPNA2 KPNB1 MAPK1 MAPK14 MAPK3 NFX1 NUP62 NUTF2 NXF1 NXF2 PTGER4 RAN SENP2 SMAD2 SMAD3 TNPO1 TPR TRN-GTT2-7 XPO1 XPO5 XPO7 XPOT	49 interacting genes: BEND7 BRWD1 CAMK2G CCDC106 CCDC150 CCDC158 CHCHD3 CHMP4A CKMT1A CKMT1B CLPP FAM50B HMG20A HMG20B KHDC4 KPNB1 KRT86 KRTAP9-8 LASP1 LCE1C LCE5A LENG1 LUC7L2 MRNIP MYOZ3 NME1 NME4 NRIP3 NUP153 NUP54 NUP62 PAX4 PBX4 PCNA PFKP PHF11 PPP1R16A PTMA RAN RPRD1B SPATC1L SPRY4 TEX35 THAP11 THAP3 TLE5 UBAP2 YAF2 ZMAT2
Entrez ID		9972	10204
HPRD ID		04899	12050
Ensembl ID		ENSG00000124789	ENSG00000102898
Uniprot IDs		P49790	A0A024R6Y2 P61970
PDB IDs		2EBQ 2EBR 2EBV 2GQE 4U0C 4U0D 5TSV 5TSX 6AYA	1GY5
Enriched GO Terms of Interacting Partners?
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