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G3BP2 and MIR16-1
Data Source:
BioGRID
(unspecified method)
G3BP2
MIR16-1
Description
G3BP stress granule assembly factor 2
microRNA 16-1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Cytoplasmic Stress Granule
Ribonucleoprotein Complex
Extracellular Space
Extracellular Exosome
Extracellular Vesicle
Molecular Function
RNA Binding
MRNA Binding
Protein Binding
Signaling Receptor Complex Adaptor Activity
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Cytoplasmic Sequestering Of NF-kappaB
Ras Protein Signal Transduction
Viral Process
Stress Granule Assembly
Innate Immune Response
MRNA Transport
Protein Homooligomerization
Positive Regulation Of Stress Granule Assembly
Branching Involved In Blood Vessel Morphogenesis
Negative Regulation Of Endothelial Cell Proliferation
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Angiogenesis
Negative Regulation Of NF-kappaB Transcription Factor Activity
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Apoptotic Process
Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Translation
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Inflammatory Response
Cellular Response To Glucose Stimulus
Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Negative Regulation Of Placenta Blood Vessel Development
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Negative Regulation Of Trophoblast Cell Migration
Negative Regulation Of Mesenchymal Stem Cell Proliferation
Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Cell Chemotaxis To Fibroblast Growth Factor
Negative Regulation Of Endothelial Cell Chemotaxis To Vascular Endothelial Growth Factor
Positive Regulation Of Connective Tissue Replacement
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
HDL cholesterol levels (
32203549
)
Response to (pegylated) interferon in HBeAg-negative hepatitis B (
30715261
)
Subjective response to lithium treatment in bipolar disorder (
26503763
)
Testicular germ cell tumor (
28604728
)
Interacting Genes
60 interacting genes:
MDM2
MIR1-1
MIR106A
MIR106B
MIR107
MIR10B
MIR128-1
MIR128-2
MIR138-2
MIR140
MIR141
MIR145
MIR155
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR19A
MIR19B1
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29B1
MIR29C
MIR31
MIR34A
MIR34B
MIR363
MIR429
MIR7-1
MIR7-2
MIR7-3
MIR92A1
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NFKB1
NFKBIA
PIN1
USP10
ZNF618
71 interacting genes:
APOBEC3B
C1QBP
CPSF7
CRTAP
DARS1
DDX1
DDX21
DDX3X
DHX36
DHX37
EIF2AK2
EPRS1
ERAL1
FAM98A
FAM98B
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KNOP1
LARP7
LIN28A
LRPPRC
MATR3
MSI2
NONO
NUDT21
PDCD11
PGAM5
PRMT1
PTBP1
PTBP3
PUF60
RARS1
RBFOX2
RBM14
RBM47
RTCA
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SUGP2
SYNCRIP
TAF15
TRA2A
TRA2B
UPF1
USP36
UTP20
YBX1
YBX2
YBX3
ZFR
ZNF346
Entrez ID
9908
406950
HPRD ID
06570
Ensembl ID
ENSG00000138757
ENSG00000208006
Uniprot IDs
A0A024RDB2
A0A024RDE5
Q9UN86
PDB IDs
5DRV
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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