CDC5L and ZRANB1

Data Source:
BioGRID (two hybrid)

		CDC5L	ZRANB1
Description		cell division cycle 5 like	zinc finger RANBP2-type containing 1
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GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm DNA Replication Factor A Complex Spliceosomal Complex Cytoplasm Membrane Nuclear Speck Perinuclear Region Of Cytoplasm U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding RNA Binding Protein Binding Protein Phosphatase 1 Binding Protein Kinase Binding Leucine Zipper Domain Binding WD40-repeat Domain Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Mitotic Cell Cycle MRNA Splicing, Via Spliceosome DNA Repair Regulation Of Transcription By RNA Polymerase II Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Interleukin-2 Signal Transduction Involved In DNA Damage Checkpoint Cellular Response To Wortmannin Cellular Response To Nerve Growth Factor Stimulus Cellular Response To Prolactin	Cytoskeleton Organization Wnt Signaling Pathway Cell Migration Protein Deubiquitination Protein Phosphopantetheinylation Regulation Of Cell Morphogenesis Positive Regulation Of Wnt Signaling Pathway Protein K29-linked Deubiquitination Protein K63-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Deubiquitination
Pathways		mRNA Splicing - Major Pathway	Degradation of beta-catenin by the destruction complex Ovarian tumor domain proteases
Drugs
Diseases
GWAS		Alzheimer disease and age of onset ( 26830138) Chin dimples ( 27182965) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) FEV1 ( 30804560) Height ( 28552196) Ischemic stroke ( 26089329) Lung function (FVC) ( 30804560) Male-pattern baldness ( 27182965) Monobrow ( 27182965) Nose morphology ( 29921221) Ossification of the posterior longitudinal ligament of the spine ( 25064007) Osteoarthritis ( 22763110) Osteoarthritis of the hand ( 28855172) Stroke (ischemic) ( 22941190) Trunk fat mass adjusted for trunk lean mass ( 32239398)	Blood urea nitrogen levels ( 31152163) Creatine kinase levels ( 29403010) Height ( 25429064 31562340)
Interacting Genes		94 interacting genes: AKAP6 AKAP9 BICRAL CALM1 CCDC136 CDC42 CDK2 CDKN1A CDKN2A CDT1 CTNNBL1 DISC1 DIXDC1 DST EMID1 ERG EXOC1 EXOC7 GOLGA2 GOLGA8EP GOLGA8F GRB14 GSE1 HNRNPM HOOK1 KALRN KANK2 KANSL1 KDM1A KIF3C KIF5B KRT18 LDOC1 LMO2 MACF1 MCM10 MCM3 MCM4 MCM5 MELK MIR106B MIR107 MIR143 MIR200B MIR214 MIR25 MIR31 MIR34A MIR34B MIR363 MIR429 MIRLET7A2 MIRLET7D MIRLET7E MIRLET7G MIRLET7I MTUS2 MYT1L ORC1 ORC2 ORC5 PCBD2 PDE4DIP PLRG1 PPFIA2 PPP1CA PPP1R13B PPP1R8 PRPF3 RPA1 RPA2 RPA3 SFR1 SH3BP5 SMARCD1 SPTBN1 SYNE1 SYNPO TP53BP2 TRAF3IP1 TRAK1 TRIO TTF2 TXLNA USHBP1 VPS52 WWC1 YWHAG YWHAQ YWHAZ ZNF35 ZNF451 ZRANB1 ZSCAN1	153 interacting genes: AKT1 ANKRD11 AP1M1 ARHGEF5 ARRDC2 ARRDC3 BAHD1 BRD1 BYSL C1orf35 CARD9 CBX7 CBX8 CCDC120 CCDC13 CCDC185 CCDC187 CCNL1 CDC45 CDC5L CDK18 CDKL3 CNNM3 CORO7 CPNE7 CSNK1A1 CWF19L2 DCX DDX6 DNAJB13 DTNB DUSP13 EHHADH EIF3D ENKD1 ERF FAIM FAM124B FAM161A FAM161B FAM214B FAM50B FARS2 FNDC11 GADD45GIP1 GAS2L2 GEM GLIS2 GPANK1 GPKOW HOXB5 HOXC8 IL16 INO80B IP6K3 IQUB JRK KANK2 KIF9 KIFC3 LENG1 LMO3 LNX1 MAGEB4 MAGOH MCRS1 METAP1 METTL21A MFAP1 MID2 MPPED1 MYEF2 NEK6 NUDT16L1 NUDT21 PBLD PHF1 PHF19 PKN1 PLEKHN1 PNMA5 POLDIP3 POLL POLR1C PPP1R18 PRPF18 PRPF3 PRPF31 PSPC1 QARS1 RAPGEF3 RASAL3 RHOBTB3 RNPS1 SDCBP SNCA STAMBPL1 STK19 SUV39H1 SYT17 SYTL4 TBC1D3 TBC1D30 TBC1D3B TBC1D3C TBC1D3G TBC1D3K TCEA2 TCEANC THAP7 TIE1 TLE5 TNS4 TOLLIP TRAF3IP3 TRAF4 TRAF6 TRAPPC2 TRAPPC2B TSGA10IP TSPYL4 TSTD2 TWIST1 UBASH3A UBC UBE2S USP2 UVRAG VAV3 VEZF1 WT1 XRCC5 ZBTB24 ZBTB47 ZNF124 ZNF17 ZNF250 ZNF408 ZNF417 ZNF438 ZNF490 ZNF497 ZNF552 ZNF575 ZNF581 ZNF587 ZNF599 ZNF629 ZNF648 ZNF764 ZNF775 ZNF792 ZNF837
Entrez ID		988	54764
HPRD ID		04184	11738
Ensembl ID		ENSG00000096401	ENSG00000019995
Uniprot IDs		Q99459	Q9UGI0
PDB IDs		2DIM 2DIN 5MQF 5XJC 5YZG 5Z56 5Z57 5Z58 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7A5P	3ZRH 5AF6
Enriched GO Terms of Interacting Partners?
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