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EIF4A3 and MEOX1
Data Source:
BioGRID
(two hybrid)
EIF4A3
MEOX1
Description
eukaryotic translation initiation factor 4A3
mesenchyme homeobox 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Membrane
Nuclear Speck
Dendrite
Exon-exon Junction Complex
Neuronal Cell Body
U2-type Catalytic Step 1 Spliceosome
Catalytic Step 2 Spliceosome
Glutamatergic Synapse
Postsynaptic Cytosol
Chromatin
Nucleus
Cytoplasm
Molecular Function
RNA Binding
RNA Helicase Activity
MRNA Binding
Protein Binding
ATP Binding
Poly(A) Binding
Selenocysteine Insertion Sequence Binding
RNA Stem-loop Binding
Ribonucleoprotein Complex Binding
Translation Regulator Activity
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific DNA Binding
HMG Box Domain Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
MRNA Splicing, Via Spliceosome
RRNA Processing
RNA Export From Nucleus
MRNA Export From Nucleus
Associative Learning
Response To Organic Cyclic Compound
Negative Regulation Of Translation
MRNA 3'-end Processing
Exploration Behavior
Positive Regulation Of Translation
Embryonic Cranial Skeleton Morphogenesis
Cellular Response To Selenite Ion
Negative Regulation Of Excitatory Postsynaptic Potential
Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission
Negative Regulation Of Selenocysteine Incorporation
Negative Regulation Of Selenocysteine Insertion Sequence Binding
Cellular Response To Brain-derived Neurotrophic Factor Stimulus
Somite Specification
Regulation Of Transcription By RNA Polymerase II
Multicellular Organism Development
Biological_process
Positive Regulation Of Transcription By RNA Polymerase II
Hematopoietic Stem Cell Differentiation
Somite Development
Sclerotome Development
Pathways
ISG15 antiviral mechanism
Transport of Mature mRNA derived from an Intron-Containing Transcript
Deadenylation of mRNA
mRNA Splicing - Major Pathway
mRNA 3'-end processing
RNA Polymerase II Transcription Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
High light scatter reticulocyte count (
32888494
27863252
)
High light scatter reticulocyte percentage of red cells (
32888494
27863252
)
Immature fraction of reticulocytes (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Myocardial infarction (
26708285
)
Reticulocyte count (
32888494
27863252
)
Reticulocyte fraction of red cells (
32888494
27863252
)
Fractures (
30158200
)
Interacting Genes
34 interacting genes:
CARD9
CASC3
CCDC174
CDCA7L
CNKSR3
CWC22
DDIT4L
DDX56
DISC1
DRG2
EHMT2
ERCC6
ESR1
HTR6
LNX1
MAGOH
MEOX1
MEOX2
NIF3L1
NXF1
PAX4
PDCD4
PICK1
POLR2G
PRMT5
PSMA1
RBM8A
REL
TRIM27
UPF1
UPF3B
VRTN
YWHAQ
ZXDB
99 interacting genes:
ACBD4
ACOT12
ALOX5
ANAPC2
APP
APPL1
ATG9A
BANP
BNIP2
BYSL
C14orf119
C1orf109
C1orf50
C2CD6
CACNB3
CCDC102B
CCDC103
CDC34
CIAO1
CIB3
CKS1B
CNOT11
CSNK2A1
CWF19L2
CYFIP1
DCX
DUSP3
EIF4A3
EIF4EBP1
EMD
FAM126B
FMR1
GCC1
GEMIN2
GPANK1
GYS1
HMBOX1
HMGB3
HOMER3
HOXC8
INPP5J
KANK2
KCTD7
L3MBTL2
LMNA
MAPK9
MBD3
MCRS1
MEF2A
MID1
MID2
MKRN3
MLX
MORF4L1
MVP
NAGK
NDOR1
NEIL2
OSGIN1
PAGE3
PARVG
PAX1
PAX3
PCP2
PDE4C
PELI2
PIN1
PLCD4
PM20D2
POLR3GL
PPM1F
PRKAG1
PRKN
QRICH1
RAD52
RANBP3
RBM41
RBM5
SDCBP
SEC14L4
SOX10
SPAG8
SPIC
SYT17
TCEANC
TCP11L1
TEX33
TRAPPC2L
TRIM41
TRIML2
TRIP10
TXLNA
TXNL4B
UBE2R2
UBXN2B
UBXN7
UNC45A
ZCCHC10
ZNF410
Entrez ID
9775
4222
HPRD ID
06482
02537
Ensembl ID
ENSG00000141543
ENSG00000005102
Uniprot IDs
A0A024R8W0
I3L3H2
P38919
P50221
PDB IDs
2HXY
2HYI
2J0Q
2J0S
2J0U
2XB2
3EX7
4C9B
5MQF
5XJC
5YZG
6ICZ
6QDV
6YVH
7A5P
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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