IFT140 and TELO2

Data Source:
BioGRID (affinity chromatography technology)

		IFT140	TELO2
Description		intraflagellar transport 140	telomere maintenance 2
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Centrosome Centriole Cilium Axoneme Intraciliary Transport Particle A Photoreceptor Connecting Cilium Ciliary Basal Body Ciliary Tip	Nucleus Cytoplasm Cytosol Membrane Nuclear Body TORC1 Complex TORC2 Complex Nuclear Periphery ASTRA Complex
	Molecular Function	Molecular_function Protein Binding	Protein Binding Protein Kinase Binding Telomeric DNA Binding Protein-containing Complex Binding Hsp90 Protein Binding Molecular Adaptor Activity
	Biological Process	Determination Of Left/right Symmetry Heart Development Regulation Of Smoothened Signaling Pathway Neural Tube Patterning Embryonic Camera-type Eye Development Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Photoreceptor Cell Outer Segment Organization Intraciliary Transport Embryonic Digit Morphogenesis Embryonic Cranial Skeleton Morphogenesis Cilium Assembly Protein Localization To Cilium Regulation Of Cilium Assembly Non-motile Cilium Assembly Embryonic Brain Development	Telomere Maintenance Via Telomerase Regulation Of TOR Signaling Protein Stabilization Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of TORC1 Signaling Positive Regulation Of TORC2 Signaling
Pathways		Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778 33020668) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)	Rheumatoid arthritis ( 30891314)
Interacting Genes		5 interacting genes: CELSR3 CRK NEK2 PFDN1 RANBP2	5 interacting genes: ATM CACNA1A KAT5 KRT15 MTOR
Entrez ID		9742	9894
HPRD ID		11093	10016
Ensembl ID		ENSG00000187535	ENSG00000100726
Uniprot IDs		Q96RY7	B4DXS2 Q9Y4R8
PDB IDs			4PSI
Enriched GO Terms of Interacting Partners?
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