IFT140 and CELSR3

Data Source:
HPRD (two hybrid)

		IFT140	CELSR3
Description		intraflagellar transport 140	cadherin EGF LAG seven-pass G-type receptor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Centrosome Centriole Cilium Axoneme Intraciliary Transport Particle A Photoreceptor Connecting Cilium Ciliary Basal Body Ciliary Tip	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Molecular_function Protein Binding	G Protein-coupled Receptor Activity Calcium Ion Binding Protein Binding
	Biological Process	Determination Of Left/right Symmetry Heart Development Regulation Of Smoothened Signaling Pathway Neural Tube Patterning Embryonic Camera-type Eye Development Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Photoreceptor Cell Outer Segment Organization Intraciliary Transport Embryonic Digit Morphogenesis Embryonic Cranial Skeleton Morphogenesis Cilium Assembly Protein Localization To Cilium Regulation Of Cilium Assembly Non-motile Cilium Assembly Embryonic Brain Development	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules G Protein-coupled Receptor Signaling Pathway Multicellular Organism Development Wnt Signaling Pathway, Planar Cell Polarity Pathway Cell-cell Adhesion
Pathways		Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778 33020668) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)	Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive ability (MTAG) ( 29186694) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Mental health study participation (provided email address) ( 31263887) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		5 interacting genes: CELSR3 CRK NEK2 PFDN1 RANBP2	12 interacting genes: CLK1 CLUH DST IFT140 SCAPER SGSM2 SPTBN2 SPTBN4 SWAP70 TRIP12 TSPYL4 UACA
Entrez ID		9742	1951
HPRD ID		11093	09179
Ensembl ID		ENSG00000187535	ENSG00000008300
Uniprot IDs		Q96RY7	Q9NYQ7
PDB IDs
Enriched GO Terms of Interacting Partners?
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