IFT140 and RAB11FIP3

Data Source:
BioGRID (affinity chromatography technology)

		IFT140	RAB11FIP3
Description		intraflagellar transport 140	RAB11 family interacting protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Photoreceptor Outer Segment Centrosome Centriole Cilium Axoneme Intraciliary Transport Particle A Photoreceptor Connecting Cilium Ciliary Basal Body Ciliary Tip	Nucleoplasm Mitochondrion Endosome Centrosome Cytosol Endocytic Vesicle Midbody Cleavage Furrow Centriolar Satellite Intracellular Membrane-bounded Organelle Intercellular Bridge Recycling Endosome Recycling Endosome Membrane
	Molecular Function	Molecular_function Protein Binding	Calcium Ion Binding Protein Binding Small GTPase Binding Protein Homodimerization Activity Dynein Light Intermediate Chain Binding
	Biological Process	Determination Of Left/right Symmetry Heart Development Regulation Of Smoothened Signaling Pathway Neural Tube Patterning Embryonic Camera-type Eye Development Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Photoreceptor Cell Outer Segment Organization Intraciliary Transport Embryonic Digit Morphogenesis Embryonic Cranial Skeleton Morphogenesis Cilium Assembly Protein Localization To Cilium Regulation Of Cilium Assembly Non-motile Cilium Assembly Embryonic Brain Development	Cell Cycle Vesicle-mediated Transport Endocytic Recycling Regulation Of Cytokinesis Cell Division Protein Localization To Cilium Negative Regulation Of Adiponectin Secretion
Pathways		Hedgehog 'off' state Intraflagellar transport	VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778 33020668) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383)	Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Heel bone mineral density ( 30598549) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494)
Interacting Genes		5 interacting genes: CELSR3 CRK NEK2 PFDN1 RANBP2	9 interacting genes: ARF4 ARF5 ARF6 ASAP1 RAB11A RAB11B RAB11FIP4 RAB25 TOMM34
Entrez ID		9742	9727
HPRD ID		11093	18521
Ensembl ID		ENSG00000187535	ENSG00000090565
Uniprot IDs		Q96RY7	O75154
PDB IDs			2D7C 2HV8 4D0M 4UJ3 4UJ4
Enriched GO Terms of Interacting Partners?
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