ULK2 and ATG14

Data Source:
BioGRID (enzymatic study)

		ULK2	ATG14
Description		unc-51 like autophagy activating kinase 2	autophagy related 14
Image
GO Annotations	Cellular Component	Cytoplasmic Vesicle Membrane Phagophore Assembly Site Membrane	Autophagosome Membrane Autophagosome Endoplasmic Reticulum Membrane Cytosol Axoneme Phagophore Assembly Site Membrane Phosphatidylinositol 3-kinase Complex, Class III Mitochondria-associated Endoplasmic Reticulum Membrane Phagocytic Vesicle Extrinsic Component Of Omegasome Membrane Extrinsic Component Of Phagophore Assembly Site Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding GTPase Binding
	Biological Process	Autophagy Signal Transduction Response To Starvation Protein Autophosphorylation Axon Extension Positive Regulation By Symbiont Of Host Autophagy	Autophagosome Assembly Mitophagy Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Endosome To Lysosome Transport Cellular Response To Starvation Posttranscriptional Regulation Of Gene Expression Macroautophagy Autophagosome Membrane Docking Cellular Response To Glucose Starvation Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Protein Complex Stability Regulation Of Triglyceride Metabolic Process Response To Mitochondrial Depolarisation
Pathways			Macroautophagy
Drugs		Fostamatinib
Diseases
GWAS			Blood protein levels ( 28240269) Eosinophil percentage of white cells ( 32888494) Platelet distribution width ( 27863252) Statin-induced myopathy ( 31220337) Testicular germ cell tumor ( 28604728) White blood cell count ( 32888494)
Interacting Genes		15 interacting genes: ATG14 DIXDC1 DUXAP9 EEF1B2 GABARAP GABARAPL2 LNX1 LUC7L2 NASP POLA2 SETDB1 SQSTM1 SYNGAP1 TNPO1 ZNF32	9 interacting genes: ATG13 EXOC1 FSD2 MIS18A RACK1 SNAPIN STX17 STYK1 ULK2
Entrez ID		9706	22863
HPRD ID		10556	13820
Ensembl ID		ENSG00000083290	ENSG00000126775
Uniprot IDs		Q8IYT8	Q6ZNE5
PDB IDs		6QAT 6QAU 6QAV 6YID	6HOL
Enriched GO Terms of Interacting Partners?
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