PGS1 and PDLIM1

Data Source:
HPRD (two hybrid)

		PGS1	PDLIM1
Description		phosphatidylglycerophosphate synthase 1	PDZ and LIM domain 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Endoplasmic Reticulum	Stress Fiber Transcription Regulator Complex Cytoplasm Cytoskeleton Adherens Junction Focal Adhesion Z Disc Filamentous Actin
	Molecular Function	Calcium Ion Binding ATP Binding CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase Activity	Transcription Coactivator Activity Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Phosphatidylglycerol Biosynthetic Process Cardiolipin Biosynthetic Process Diacylglycerol Metabolic Process	Response To Hypoxia Regulation Of Transcription By RNA Polymerase II Response To Oxidative Stress Heart Development Fibroblast Migration Maintenance Of Cell Polarity Actin Cytoskeleton Organization Establishment Or Maintenance Of Actin Cytoskeleton Polarity Stress Fiber Assembly Positive Regulation Of Transcription, DNA-templated Muscle Structure Development Cell-cell Adhesion
Pathways		Synthesis of PG
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) HDL cholesterol ( 24097068 30275531 25961943 20686565) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Heel bone mineral density ( 30598549) Hemoglobin ( 32888494) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) LDL cholesterol ( 30275531) LDL cholesterol levels ( 32203549) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin concentration ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolic syndrome ( 31589552) Plateletcrit ( 32888494) Red cell distribution width ( 32888494) Total cholesterol levels ( 30275531) Triglyceride levels ( 32203549 32154731) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglycerides ( 30275531)	Hemoglobin ( 32888494) Mean platelet volume ( 32888494 27863252) Suicide risk ( 21041247) White blood cell count ( 32888494)
Interacting Genes		2 interacting genes: GABARAP PDLIM1	14 interacting genes: ACTN1 ACTN2 ACTN4 AGK GFAP MAPK6 PGS1 PITX2 PTGER4 RLIM RPS6KA5 STK35 SUPT4H1 VIM
Entrez ID		9489	9124
HPRD ID		17841	09326
Ensembl ID		ENSG00000087157	ENSG00000107438
Uniprot IDs		A0A024R8V5 B4DLU3 Q32NB8	O00151 V9HW92
PDB IDs			1X62 2PKT
Enriched GO Terms of Interacting Partners?
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