NAPSA and LCE1B

Data Source:
BioGRID (two hybrid)

		NAPSA	LCE1B
Description		napsin A aspartic peptidase	late cornified envelope 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Lysosome Extracellular Exosome Alveolar Lamellar Body Multivesicular Body Lumen
	Molecular Function	Endopeptidase Activity Aspartic-type Endopeptidase Activity Protein Binding Peptidase Activity	Protein Binding Identical Protein Binding
	Biological Process	Proteolysis Membrane Protein Proteolysis Surfactant Homeostasis Cellular Protein Metabolic Process	Keratinization
Pathways		Surfactant metabolism	Formation of the cornified envelope
Drugs
Diseases
GWAS			Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		1 interacting genes: LCE1B	72 interacting genes: ADAMTSL4 BEND5 CYSRT1 FBLN1 FUCA2 HOXA1 KRT31 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP3-1 KRTAP3-2 KRTAP4-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE4A LCE5A MDFI MEOX2 NAPSA NBPF19 NOTCH2NLA NUFIP2 OTX1 P4HB RGS17 RGS20 RNF4 SMCP SPRY1 SPRY2 SPRY3 TGM1 TRIM42
Entrez ID		9476	353132
HPRD ID		07064	17259
Ensembl ID		ENSG00000131400	ENSG00000196734
Uniprot IDs		O96009	Q5T7P3
PDB IDs
Enriched GO Terms of Interacting Partners?
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