PICK1 and BRD1

Data Source:
BioGRID (two hybrid)

		PICK1	BRD1
Description		protein interacting with PRKCA 1	bromodomain containing 1
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GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Plasma Membrane Synaptic Vesicle Postsynaptic Density Endocytic Vesicle Membrane Trans-Golgi Network Membrane Presynaptic Membrane Neuron Projection Synapse Perinuclear Region Of Cytoplasm Postsynaptic Early Endosome	Nucleus Chromosome Nuclear Speck Dendrite Histone H3-K14 Acetyltransferase Complex Perikaryon MOZ/MORF Histone Acetyltransferase Complex
	Molecular Function	G Protein-coupled Receptor Binding Protein Kinase C Binding Signaling Receptor Binding Protein Binding Phospholipid Binding Protein C-terminus Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Metal Ion Binding Actin Filament Binding Arp2/3 Complex Binding Membrane Curvature Sensor Activity	Protein Binding Histone Binding Histone Acetyltransferase Activity (H3-K23 Specific) Metal Ion Binding
	Biological Process	Positive Regulation Of Receptor Internalization Protein Phosphorylation Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Monoamine Transport Glial Cell Development Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cellular Response To Decreased Oxygen Levels Cellular Response To Glucose Starvation DNA Methylation Involved In Embryo Development DNA Methylation Involved In Gamete Generation Receptor Clustering Neuronal Ion Channel Clustering Regulation Of Insulin Secretion Long-term Synaptic Depression Dendritic Spine Organization Dendritic Spine Maintenance	Response To Immobilization Stress Erythrocyte Maturation Histone H3 Acetylation Histone H3-K23 Acetylation Histone H3-K14 Acetylation Positive Regulation Of Erythrocyte Differentiation Response To Electrical Stimulus
Pathways		Cell surface interactions at the vascular wall Trafficking of GluR2-containing AMPA receptors	HATs acetylate histones Regulation of TP53 Activity through Acetylation
Drugs
Diseases
GWAS		Body fat percentage ( 26833246) Brain morphology (MOSTest) ( 32665545) Mean platelet volume ( 32888494)	Acne (severe) ( 24927181) Mean platelet volume ( 27863252) Metabolite levels ( 23823483) Natriuretic peptide levels ( 21273288) Pulse pressure ( 30224653) Schizophrenia ( 23894747) Urinary albumin excretion ( 32277301) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		365 interacting genes: ABT1 AEBP2 AFDN AKT1 AKT2 ALKBH8 AP1M1 AP1S1 APTX AQP1 ARF1 ARF3 ARHGEF3 ARHGEF5 ARL6IP1 ARMCX1 ASIC1 ASIC2 ATP5IF1 ATXN1L ATXN3 ATXN7 ATXN7L3 AVPI1 BAHD1 BCL2L14 BEX1 BLK BLOC1S2 BOLA3 BRD1 BTG2 BUD31 BYSL C1orf35 C2CD5 C4orf46 C8orf33 CARD9 CBX8 CCDC102B CCDC103 CCDC187 CCNH CDC42EP2 CDC73 CDCA7L CDK2AP1 CDKL3 CDKN2B CDKN2D CEP19 CEP290 CEP57L1 CEP89 CEP95 CGGBP1 CHMP1B CIC COIL CPNE2 CPNE7 CRY2 CSNK2A2 CTNNB1 CTSG CUTC CWF19L2 CYP21A2 DCTD DCUN1D5 DDX55 DDX6 DMC1 DMD DNAJB13 DNTTIP1 DNTTIP2 DPF2 DRAP1 DTNB DUSP29 EAF1 EEF2KMT EFHC2 EFNB1 EFNB2 EHD2 EHHADH EIF1AD EIF3D EIF4A3 EIF4EBP1 EIF4H EIF5A ENKD1 EPHB2 EPM2AIP1 ERBB2 ERBIN ESCO2 EXOSC5 F11R FAM161A FAM161B FAM207A FAM214B FAM219B FAM90A1 FAM9A FBXL3 FBXL8 FGF16 FKBP6 FLYWCH1 FXN GADD45GIP1 GAS2L2 GFI1 GFI1B GLYCTK GPATCH11 GPATCH2 GPC4 GPKOW GRB10 GRB7 GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIP1 GRM3 GRM7 GRXCR1 GTF2E2 GTPBP2 HDAC4 HEXIM2 HMBOX1 HMBS HMG20A HOPX HOXA5 HSD17B14 HSF2 HSF2BP ID2 IHO1 IL16 ILF2 INO80B INO80E INPP5J IP6K1 ISCU JAM3 JRK KAT5 KCTD1 KCTD6 KCTD9 KIAA1328 L3MBTL2 LCLAT1 LCN2 LGALS14 LMO1 LMO3 LONRF1 LRP2BP LRRC73 LZTFL1 LZTS1 MAGEA4 MAGEB4 MAP2K6 MAPK9 MAPRE3 MAZ MBD3 MCM10 MEOX2 MGME1 MID2 MNS1 MOB3C MORF4L1 MORF4L2 MORN3 MOS MRI1 MRNIP MSRB3 MSS51 MTA1 MTG1 NATD1 NCOA5 NDEL1 NECAB2 NECTIN2 NECTIN4 NEK6 NME7 NMNAT1 NOC4L OARD1 OPTN OSBP2 OSGIN1 OSTF1 PAFAH1B3 PAX6 PBX4 PCBD1 PDCD5 PDS5A PEBP1 PHF19 PIBF1 PKN1 PKNOX2 PLEKHA7 PNKP PNO1 POLL POLR3C PPARA PPL PRKCA PRKCG PRKN PRLHR PRPF18 PRPF31 PRPF40A PSMA1 PSME3 PTRH1 QARS1 RAD51D RASAL3 REEP6 REL RFC3 RIMS3 RIN1 RNF8 RNPS1 ROBO3 ROPN1 RPIA RPP25 RRP8 RXRB RXRG SACS SCAND1 SCNM1 SEMA3B SEPTIN1 SERBP1 SERTAD1 SERTAD3 SH2D4A SH3GLB2 SHFL SLC6A3 SLIRP SMARCB1 SMARCD1 SNRNP25 SNRPA1 SNRPB2 SNW1 SPANXN2 SPATC1L SPEG SSNA1 STK19 STK4 SYT17 TBC1D22B TBC1D26 TBC1D7 TCEA2 TCEANC TCEANC2 TDO2 TEX101 TFIP11 THAP6 THAP7 TLE5 TLNRD1 TPM4 TRAF4 TRAF5 TRIM44 TRIM54 TRIML2 TRMT2A TSGA10IP TSN TSTD2 TTC23 TTC23L TXNDC9 TXNL4B TYW3 UBE2E3 UBE2K UBQLN4 USHBP1 USP2 USP7 UTP3 VAX1 VEZF1 VPS25 WT1 XPA YES1 YPEL2 YTHDC1 ZBED1 ZBTB2 ZBTB24 ZBTB49 ZFHX3 ZFP2 ZFP91 ZMAT2 ZMYND12 ZNF165 ZNF17 ZNF205 ZNF250 ZNF264 ZNF276 ZNF286A ZNF329 ZNF330 ZNF35 ZNF408 ZNF410 ZNF414 ZNF417 ZNF438 ZNF497 ZNF524 ZNF575 ZNF576 ZNF593 ZNF624 ZNF691 ZNF71 ZNF764 ZNF774 ZSCAN21 ZSCAN23 ZZZ3	17 interacting genes: CASP8 CEP126 CEP70 DISC1 FEZ1 FEZ2 H2AX H3C14 HMBOX1 MAGEA11 PICK1 RUBCN SS18L1 TFIP11 VIM ZNF512B ZRANB1
Entrez ID		9463	23774
HPRD ID		16176	06848
Ensembl ID		ENSG00000100151	ENSG00000100425
Uniprot IDs		A0A024R1J5 Q9NRD5	A0A024R4V5 A0A024R4W4 O95696 Q59G93
PDB IDs		2GZV 6AR4 6BJN 6BJO	2KU3 2L43 2LQ6 3LYI 3RCW 4Z02 5AME 5AMF 5FG6 5GK9 5N49 5PNX 5PNY 5PNZ 5PO0 5PO1 5PO2 5PO3 5PO4 5PO5 5PO6 5PO7 5PO8 5PO9 5POA 5POB 5POC 5POD 5POE 5POF 5POG 5POH 5POI 5POJ 5POK 5POL 5POM 5PON 5POO 5POP 5POQ 5POR 5POS 5POT 5POU 5POV 5POW 5POX 5POY 5POZ 5PP0 5PP1 5PP2 5PP3 5PP4 5PP5 5PP6 5PP7 5PP8 5PP9 5PPA 5PPB 5PPC 5PPD 5PPE 5PPF 5PPG 5PPH 5PPI 5PPJ 5PPK 5PPL 5PPM 5PPN 5PPO 5PPP 5PPQ 5PPR 5PPS 5PPT 5PPU 5PPV 5PPW 5PPX 5PPY 5PPZ 5PQ0 5PQ1 5PQ2 5PQ3 5PQ4 5PQ5 5PQ6 5PQ7 5PQ8 5PQ9 5PQA 5PQB 5PQC 5PQD 5PQE 5PQF 5PQG 5PQH 5PQI 5PQJ 5PQK 5PQL 5PQM 5PQN 5PQO 5PQP 5PQQ 5PQR 5PQS 5PQT 5PQU 5PQV 5PQW 5PQX 5PQY 5PQZ 5PR0 5PR1 5PR2 5PR4 5PR5 5PR6 5PR7 5PR8 5PR9 5PRA 5PRB 5PRD 5PRE 5PRF 5PRG 5PRH 5PRI 5PRJ 5PRK 5PRL 5PRM 5PRO 5PRP 5PRQ 5PRR 5PRS 5PRT 5PRU 5PRV 5PRW 5PRX 5PRY 5PRZ 5PS0 5PS1 5PS2 5PS3 5PS4 5PS5 5PS6 5PS7 5PS8 5PS9 5PSA 5PSB 5PSC 5PSD 5PSE 5PSF 5PSG 5PSH 5PSI 5PSJ 5PSK 5PSL 5PSM 5PSN 5PSO 5PSP 5PSQ 5PSR 5PSS 5PST 5PSU 5PSV 5PSW 5PSX 5PSY 5PSZ 5PT0 5PT1 5PT2 5PT3 5PT4 5PT5 5PT6 5PT7 5PT8 5PT9 5PTA 5PTB 5PTC 5PTE 5PTF 5PTG 5PTH 5PTJ 5PTK 5PTL 5PTM 5PTN 5PTO 5PTQ 5PTR 5PTS 5PTT 5PTU 5PTV 5PTW 5PTX 5PTY 5PTZ 5PU0 5PU1 5PU2 5PU3 5PU4 5PU5 5PU6 5PU7 5PU8 5PU9 5PUA 5PUB 5PUC 5PUD 5PUE 5PUF 5PUG 5PUH 5PUI 5PUJ 5PUK 5PUL 5PUM 5PUN 5PUO 5PUP 5PUQ 5PUR 5PUS 5PUT 5PUU 5PUV 5PUW 5PUX 5PUY 5PUZ 5PV0 5PV1 5PV2 5PV3 5PV4 5PV5 5PV6 5PV7 5PV8 5PV9 5PVA 5PVB 5PVC 5PVD 5PVE 5PVF 5PVG 5PVH 5PVI 5PVJ 5PVK 5PVL 5PVM 5PVN 5PVO 5PVP 5PVQ 5PVR 5PVS 5PVT 5PVU 5PVV 5PVW 5PVX 5PVY 5PVZ 5PW0 5PW1 5PW2 5PW3 5PW4 5PW5 5PW6 5PW7 5PW8 5PW9 5PWA 5PWB 6IN2 6MAJ 6MAK
Enriched GO Terms of Interacting Partners?
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