MED23 and ELF3

Data Source:
HPRD (in vitro)

		MED23	ELF3
Description		mediator complex subunit 23	E74 like ETS transcription factor 3
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GO Annotations	Cellular Component	Nucleoplasm Transcription Regulator Complex Mediator Complex	Chromatin Nucleus Nucleoplasm Golgi Apparatus Cytosol
	Molecular Function	Transcription Coactivator Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated	Blastocyst Development Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Inflammatory Response Cell Differentiation Extracellular Matrix Organization Epithelial Cell Differentiation Positive Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Mammary Gland Involution
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Pre-NOTCH Transcription and Translation
Drugs
Diseases
GWAS		L-arginine levels ( 25245031) Type 2 diabetes ( 30054458)
Interacting Genes		15 interacting genes: CEBPB CTDP1 ELF3 ESR1 ESR2 ETS1 FOXJ3 MED13 MED9 NCOA6 PUM2 RELA SREBF1 VDR WDTC1	15 interacting genes: AR CREBBP EGFR EP300 EPS15 JUN MED23 MYC NFKB1 PAK1 SOX9 TAF9 TBP XRCC5 XRCC6
Entrez ID		9439	1999
HPRD ID		05436	03722
Ensembl ID		ENSG00000112282	ENSG00000163435
Uniprot IDs		Q05DL5 Q9ULK4	A0A024R974 P78545
PDB IDs		6H02	2E8P
Enriched GO Terms of Interacting Partners?
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