ARHGAP29 and PTPN13

Data Source:
HPRD (in vitro)

		ARHGAP29	PTPN13
Description		Rho GTPase activating protein 29	protein tyrosine phosphatase non-receptor type 13
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Protein-containing Complex	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Lamellipodium Neuron Projection Cell Body Extracellular Exosome
	Molecular Function	GTPase Activator Activity PDZ Domain Binding Metal Ion Binding	Protein Tyrosine Phosphatase Activity Protein Binding Phosphatidylinositol 3-kinase Regulatory Subunit Binding
	Biological Process	Rho Protein Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity	Negative Regulation Of Protein Phosphorylation Protein Dephosphorylation Phosphatidylinositol Biosynthetic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Peptidyl-tyrosine Dephosphorylation Cellular Response To Cytokine Stimulus
Pathways		Rho GTPase cycle	Synthesis of PIPs at the plasma membrane Interleukin-37 signaling
Drugs
Diseases
GWAS		Cleft lip with or without cleft palate ( 28054174) D-dimer levels ( 21502573) Orofacial clefts ( 28054174) Plateletcrit ( 32888494) Systolic blood pressure ( 30224653)	Eyebrow thickness ( 26926045) Hemoglobin levels ( 32327693) Kidney disease (end stage renal disease vs non-end stage renal disease) in type 1 diabetes ( 27647854) Kidney disease (end stage renal disease vs normoalbuminuria) in type 1 diabetes ( 27647854) Word spelling ( 30741946)
Interacting Genes		7 interacting genes: HRAS KDM1A MAGEA11 PTPN13 RAP2A RHOA TRIM54	24 interacting genes: APC ARHGAP29 BEX3 BRD7 CRHR1 CRIP2 CTNNB1 EFNB1 EFNB2 FADD FAS FASLG GHR MTNR1A NFKBIA NGFR PDLIM4 PKN2 PLEKHA1 PLEKHA2 PRKACA RAPGEF6 TRIP6 YWHAZ
Entrez ID		9411	5783
HPRD ID		06674	02602
Ensembl ID		ENSG00000137962	ENSG00000163629
Uniprot IDs		Q52LW3	Q12923
PDB IDs			1D5G 1Q7X 1WCH 2M0Z 2M10 3LNX 3LNY 3PDZ 5GLJ
Enriched GO Terms of Interacting Partners?
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