ORMDL1 and COQ9

Data Source:
BioGRID (two hybrid)

		ORMDL1	COQ9
Description		ORMDL sphingolipid biosynthesis regulator 1	coenzyme Q9
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane SPOTS Complex	Mitochondrion Mitochondrial Inner Membrane
	Molecular Function	Protein Binding	Protein Binding Lipid Binding Protein Homodimerization Activity
	Biological Process	Ceramide Metabolic Process Cellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process	Mitochondrial Electron Transport, NADH To Ubiquinone Ubiquinone Biosynthetic Process
Pathways		Sphingolipid de novo biosynthesis	Ubiquinol biosynthesis
Drugs
Diseases			Coenzyme Q10 deficiency
GWAS		Bilirubin levels ( 20639394) Ferritin levels ( 25162662)
Interacting Genes		37 interacting genes: APP AQP6 ARL13B ASGR2 COQ9 CPLX4 CREB3 CREB3L1 EBAG9 EBP EHHADH ERGIC3 GPR152 HSD17B11 KCNK4 LMNA LNX1 MFSD14B PCNX2 PGRMC2 REEP4 SAR1A SCN3B SLC10A1 SLC10A6 SLC18A1 SLC30A8 SLC35C2 STOM TLCD4 TMEM143 TMEM14B TMEM35A TMEM52B VMA21 ZDHHC15 ZFYVE27	33 interacting genes: ACSF2 ACTL6B ADIPOQ ALDH18A1 ANO8 BMP10 CCL4L2 CLNK COQ4 COQ8A CTSA CTXN3 CYB561D2 CYBC1 EHHADH GALNT2 HMOX1 KIR2DL3 MGLL ORMDL1 PLSCR2 SCARF1 SLC13A1 STX3 TEX264 TMEM14C TMEM79 TMEM86A TNFRSF10C TRAF3IP3 TSPAN33 VSTM1 WFDC2
Entrez ID		94101	57017
HPRD ID		15092	13157
Ensembl ID		ENSG00000128699	ENSG00000088682
Uniprot IDs		Q9P0S3	A0A024R6U3 O75208
PDB IDs			4RHP 6AWL 6DEW
Enriched GO Terms of Interacting Partners?
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