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MRFAP1 and BRK1
Data Source:
BioGRID
(two hybrid)
MRFAP1
BRK1
Description
Morf4 family associated protein 1
BRICK1 subunit of SCAR/WAVE actin nucleating complex
Image
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Perinuclear Region Of Cytoplasm
Cytosol
Cytoskeleton
Lamellipodium
SCAR Complex
Extracellular Exosome
Molecular Function
Protein Binding
Protein Binding
Small GTPase Binding
Identical Protein Binding
Protein-containing Complex Binding
Biological Process
In Utero Embryonic Development
Actin Filament Organization
Regulation Of Actin Polymerization Or Depolymerization
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Lamellipodium Assembly
Rac Protein Signal Transduction
Positive Regulation Of Protein-containing Complex Assembly
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cell Motility
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
VEGFA-VEGFR2 Pathway
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS
Arterial stiffness index (
31235810
)
Interacting Genes
41 interacting genes:
ABI1
ABI2
ABI3
BRK1
C14orf93
C3orf62
C8orf33
CAVIN3
CCDC146
DCDC2
DNAJB5
DPY30
FCHSD2
GOLGA8F
GOLGA8G
HTT
KIFC3
MAP1LC3B
MORF4L1
MORF4L2
MRFAP1L1
MTIF3
PAM16
PCBD2
PRAP1
PRKAA2
SDCBP
SH2D4A
SMU1
SUV39H2
TEX11
TK1
TPM2
TRIM47
TXN
TXN2
UBTD1
UQCC2
WASHC1
ZDHHC17
ZNF655
10 interacting genes:
BRAP
CYFIP2
HSBP1
MRFAP1
NCK1
NCKAP1
NDEL1
PFDN1
PIK3R3
WASF1
Entrez ID
93621
55845
HPRD ID
17589
12818
Ensembl ID
ENSG00000179010
ENSG00000254999
Uniprot IDs
A0A087WTY9
B3KQA0
Q9Y605
Q8WUW1
PDB IDs
3P8C
4N78
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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