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TPTE2 and LMTK2
Data Source:
BioGRID
(two hybrid)
TPTE2
LMTK2
Description
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2
lemur tyrosine kinase 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Nucleus
Endoplasmic Reticulum Membrane
Cytosol
Plasma Membrane
Integral Component Of Membrane
Cell Projection
Early Endosome
Golgi Apparatus
Cytosol
Integral Component Of Plasma Membrane
Integral Component Of Membrane
Growth Cone
Neuronal Cell Body
Receptor Complex
Perinuclear Region Of Cytoplasm
Recycling Endosome
Molecular Function
Protein Tyrosine Phosphatase Activity
Protein Tyrosine/serine/threonine Phosphatase Activity
Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity
Protein Serine/threonine Kinase Activity
Transmembrane Receptor Protein Tyrosine Kinase Activity
Protein Phosphatase Inhibitor Activity
Protein Binding
ATP Binding
Myosin VI Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
Protein Dephosphorylation
Phosphatidylinositol Biosynthetic Process
Negative Regulation Of Cell Population Proliferation
Phosphatidylinositol 3-kinase Signaling
Dephosphorylation
Peptidyl-tyrosine Dephosphorylation
Phosphatidylinositol Dephosphorylation
Cell Motility
Regulation Of Protein Kinase B Signaling
Receptor Recycling
Protein Phosphorylation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Multicellular Organism Development
Axonogenesis
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Peptidyl-tyrosine Phosphorylation
Endocytic Recycling
Negative Regulation Of Phosphoprotein Phosphatase Activity
Transferrin Transport
Positive Regulation Of Kinase Activity
Early Endosome To Late Endosome Transport
Protein Autophosphorylation
Pathways
Synthesis of PIPs at the Golgi membrane
Drugs
Diseases
GWAS
Liver fibrosis (total hepatic collagen content) (
32953199
)
Gamma glutamyl transferase levels (
29403010
)
Hemoglobin levels (
32327693
)
Prostate cancer (
18264097
)
Interacting Genes
5 interacting genes:
AATK
BRCA1
EPHA2
LMTK2
PTK7
24 interacting genes:
CDC14A
CDC25C
CDK5
CDK5R1
DUSP14
DUSP19
DUSP29
DUSP6
ILKAP
MTMR6
PPM1A
PPM1F
PPM1K
PPP1CA
PPP1CB
PPP1CC
PPP1R2
PPP3CB
PTPDC1
PTPN12
PTPN6
PTPRR
STYX
TPTE2
Entrez ID
93492
22853
HPRD ID
06003
13994
Ensembl ID
ENSG00000132958
ENSG00000164715
Uniprot IDs
Q6XPS3
Q8IWU2
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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