TIFA and TIFAB

Data Source:
HPRD (in vivo)

		TIFA	TIFAB
Description		TRAF interacting protein with forkhead associated domain	TIFA inhibitor
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Binding
	Biological Process	Cytoplasmic Pattern Recognition Receptor Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Protein Homooligomerization	I-kappaB Kinase/NF-kappaB Signaling Thorax And Anterior Abdomen Determination Trigeminal Nerve Development Vestibulocochlear Nerve Formation Peristalsis Auditory Behavior Genitalia Morphogenesis Inner Ear Morphogenesis Regulation Of Muscle Organ Development Genitalia Development Inner Ear Development Neuromuscular Process Controlling Balance Mastication Cochlea Development Cochlea Morphogenesis Craniofacial Suture Morphogenesis Learned Vocalization Behavior Negative Regulation Of Relaxation Of Muscle Negative Regulation Of Saliva Secretion Hard Palate Morphogenesis
Pathways		Alpha-protein kinase 1 signaling pathway
Drugs
Diseases
GWAS		Body mass index ( 26426971) Rheumatoid arthritis ( 30891314)	Coronary artery aneurysm in Kawasaki disease ( 30267110)
Interacting Genes		23 interacting genes: AP1M1 ARHGEF39 DVL2 GSDME IRAK1 KANK2 LNX1 LNX2 NIF3L1 NTAQ1 NUDT18 NXF1 PRKAA2 RIPPLY3 RPL9 SDCBP SDCBP2 TIFAB TNFAIP8 TRAF1 TRAF2 TRAF6 TXN2	1 interacting genes: TIFA
Entrez ID		92610	497189
HPRD ID		09835	19341
Ensembl ID		ENSG00000145365	ENSG00000255833
Uniprot IDs		Q96CG3	Q6ZNK6
PDB IDs		4YM4 4ZGI 5ZUJ 6A33
Enriched GO Terms of Interacting Partners?
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