CRB3 and BET1

Data Source:
BioGRID (two hybrid)

		CRB3	BET1
Description		crumbs cell polarity complex component 3	Bet1 golgi vesicular membrane trafficking protein
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GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Apical Plasma Membrane Cell Junction Protein-containing Complex Extracellular Exosome	Golgi Trans Cisterna Golgi Membrane Endoplasmic Reticulum Membrane Membrane Transport Vesicle Integral Component Of Golgi Membrane SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding SH3 Domain Binding Protein Domain Specific Binding	SNAP Receptor Activity Protein Binding
	Biological Process	Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Positive Regulation Of Cell Junction Assembly	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport COPII Vesicle Coating Vesicle Fusion With Golgi Apparatus
Pathways		Tight junction interactions	COPII-mediated vesicle transport COPI-mediated anterograde transport
Drugs
Diseases
GWAS			Aging ( 22773346) Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655) BRCA1/2-negative high-risk breast cancer ( 30323354) Obesity-related traits ( 23251661) World class endurance athleticism ( 26824906)
Interacting Genes		28 interacting genes: ANKRD46 BCL2L13 BET1 FUNDC2 HMOX1 HMOX2 NDUFA3 PALS1 PARD6A PATJ PLLP PLP2 PSENEN PSMA3 RABAC1 SERF1A SERF1B SERP1 SLC39A9 STX5 TECR TMEM222 TREX1 UBIAD1 VAMP1 VTI1B WDR83 YIPF6	52 interacting genes: ADORA2A ANKS6 AQP6 ASGR2 ASZ1 BCL2L13 CD74 CD79A CGRRF1 CISD2 CLDN7 CLEC10A CRB3 CREB3L1 CYB561 CYBC1 ELOVL4 ERGIC3 FAM174A FAM209A FAM210B FAM9B GOSR2 GPR152 GPX8 JAGN1 KASH5 KCNJ6 LYPD5 MAGEA6 MFF MGST3 NAPB PTGES REEP4 RETREG3 SLC26A6 SLC7A14 SNTG2 SSMEM1 STX1A STX1B STX2 STX4 STX5 TMCO5A TMEM237 TMEM35A TMEM52B TMEM80 TMX2 USHBP1
Entrez ID		92359	10282
HPRD ID		16749	16107
Ensembl ID		ENSG00000130545	ENSG00000105829
Uniprot IDs		Q9BUF7	O15155 Q53XK0
PDB IDs		5I7Z	3EGX
Enriched GO Terms of Interacting Partners?
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