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BTF3L4 and SMYD2
Data Source:
BioGRID
(two hybrid)
BTF3L4
SMYD2
Description
basic transcription factor 3 like 4
SET and MYND domain containing 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
Protein Binding
RNA Polymerase II Complex Binding
P53 Binding
Protein Binding
Lysine N-methyltransferase Activity
Protein-lysine N-methyltransferase Activity
Histone-lysine N-methyltransferase Activity
Metal Ion Binding
Histone Methyltransferase Activity (H3-K36 Specific)
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Heart Development
Negative Regulation Of Cell Population Proliferation
Histone H3-K36 Methylation
Peptidyl-lysine Monomethylation
Peptidyl-lysine Dimethylation
Histone Lysine Methylation
Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
PKMTs methylate histone lysines
Regulation of TP53 Activity through Methylation
Drugs
Diseases
GWAS
Abdominal aortic aneurysm (
27899403
)
Diverticular disease (
30177863
)
Interacting Genes
4 interacting genes:
NOTCH3
SMYD2
TXLNA
TXLNB
8 interacting genes:
BTF3
BTF3L4
ESR1
H3C14
HSP90AA1
RB1
SNX11
TP53
Entrez ID
91408
56950
HPRD ID
17521
15406
Ensembl ID
ENSG00000134717
ENSG00000143499
Uniprot IDs
Q96K17
Q9NRG4
PDB IDs
3RIB
3S7B
3S7D
3S7F
3S7J
3TG4
3TG5
4O6F
4WUY
4YND
5ARF
5ARG
5KJK
5KJL
5KJM
5KJN
5V3H
5WCG
6CBX
6CBY
6MON
6N3G
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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