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USP8 and NBR1
Data Source:
BioGRID
(pull down)
USP8
NBR1
Description
ubiquitin specific peptidase 8
NBR1 autophagy cargo receptor
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Early Endosome
Cytosol
Postsynaptic Density
Extrinsic Component Of Plasma Membrane
Midbody
Extrinsic Component Of Endosome Membrane
Dendritic Spine
Glutamatergic Synapse
Phagophore Assembly Site
Nucleoplasm
Mitochondrion
Mitochondrial Intermembrane Space
Lysosome
Late Endosome
Autophagosome
Cytosol
Membrane
Nuclear Body
M Band
Intracellular Membrane-bounded Organelle
Receptor Complex
Molecular Function
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
SH3 Domain Binding
Cadherin Binding
Protein Binding
Zinc Ion Binding
Ubiquitin Binding
Mitogen-activated Protein Kinase Binding
Biological Process
Mitotic Cytokinesis
Ubiquitin-dependent Protein Catabolic Process
Endosome Organization
Ras Protein Signal Transduction
Protein Deubiquitination
Protein Phosphopantetheinylation
Regulation Of Protein Stability
Regulation Of Protein Localization
Protein K63-linked Deubiquitination
Protein K48-linked Deubiquitination
Cellular Response To Dexamethasone Stimulus
Positive Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission
Cellular Response To Nerve Growth Factor Stimulus
Macroautophagy
Regulation Of Bone Mineralization
Regulation Of Stress-activated MAPK Cascade
Negative Regulation Of Osteoblast Differentiation
Pathways
Downregulation of ERBB2:ERBB3 signaling
Regulation of FZD by ubiquitination
Ub-specific processing proteases
Negative regulation of MET activity
Pexophagy
Pexophagy
Drugs
Diseases
GWAS
Ankylosing spondylitis (
30946743
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Heel bone mineral density (
30598549
)
Mean reticulocyte volume (
32888494
)
Monocyte percentage of white cells (
32888494
)
Interacting Genes
40 interacting genes:
BACE1
BIRC6
CFLAR
CHMP1A
CHMP1B
CHMP2A
CHMP2B
CHMP4C
CHMP7
DNAJB6
EPS15
GRAP2
GRB2
H2AC20
H2BC21
KIF23
NBR1
PJA1
PLA2G2A
RASGRF1
RNF41
SEC31A
SHANK1
SHANK3
SLBP
SNCA
SPP1
SRC
STAM
STAM2
TRIM54
TRIM55
TRIM63
UBC
USP15
USP21
USP28
YWHAG
YWHAQ
YWHAZ
22 interacting genes:
ATXN1L
AXIN1
CALM1
CIB1
FEZ1
GABARAP
GABARAPL2
GSK3A
GSK3B
ITSN2
MAP1LC3A
MAP1LC3B
MAP2K4
METAP1
SQSTM1
SYT4
TTN
UBC
UBE2D2
UBE2D3
USP8
VTA1
Entrez ID
9101
4077
HPRD ID
04405
01326
Ensembl ID
ENSG00000138592
ENSG00000188554
Uniprot IDs
A0A024R5S4
A8K8N5
P40818
A0A024R1V3
B7Z5R6
Q14596
PDB IDs
1WHB
2A9U
2GFO
2GWF
3N3K
6F09
1WJ6
2BKF
2CP8
2G4S
2L8J
2MGW
2MJ5
4OLE
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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