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CLDN2 and GRM2
Data Source:
BioGRID
(two hybrid)
CLDN2
GRM2
Description
claudin 2
glutamate metabotropic receptor 2
Image
GO Annotations
Cellular Component
Plasma Membrane
Cell-cell Junction
Bicellular Tight Junction
Integral Component Of Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Axon
Dendrite
Presynaptic Membrane
Astrocyte Projection
Integral Component Of Postsynaptic Membrane
Molecular Function
Structural Molecule Activity
Protein Binding
Identical Protein Binding
Adenylate Cyclase Inhibiting G Protein-coupled Glutamate Receptor Activity
Group II Metabotropic Glutamate Receptor Activity
G Protein-coupled Receptor Activity
Calcium Channel Regulator Activity
Protein Binding
Glutamate Receptor Activity
Scaffold Protein Binding
Biological Process
Cell Adhesion
Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules
Bicellular Tight Junction Assembly
G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway
G Protein-coupled Glutamate Receptor Signaling Pathway
Chemical Synaptic Transmission
Gene Expression
Glutamate Secretion
Regulation Of Protein Kinase B Signaling
Regulation Of Synaptic Transmission, Glutamatergic
Glutamate Homeostasis
Pathways
Tight junction interactions
G alpha (i) signalling events
Class C/3 (Metabotropic glutamate/pheromone receptors)
Drugs
LY2140023
Diseases
GWAS
Alcoholic chronic pancreatitis (
28754779
)
Pancreatitis (
23143602
)
Interacting Genes
29 interacting genes:
ADAM33
BTN3A2
CLEC2D
CSGALNACT2
CXCL9
CYSRT1
EMP3
FAM209A
GRM2
IGFBP5
IL27RA
KRT31
KRTAP1-1
KRTAP1-3
KRTAP10-3
KRTAP4-12
LAT
LNX1
LPAR3
MTDH
NOTCH2NLA
PIAS2
PLP1
TEX264
TJP1
TJP2
TMEM218
UBE2I
WNK4
29 interacting genes:
ACBD5
AQP6
BIK
CCDC107
CLDN2
CLDN9
CPLX4
CYB5R3
GNA15
GNAQ
GRIP1
LMNA
MFSD14B
MGST3
MMGT1
NAALADL2
PDZK1IP1
RGS12
SAR1A
SDCBP
SLC30A8
SLC38A1
STOM
TAMALIN
TMEM130
TMEM237
TMEM248
TSPAN18
UBQLN1
Entrez ID
9075
2912
HPRD ID
06471
04977
Ensembl ID
ENSG00000165376
ENSG00000164082
Uniprot IDs
P57739
Q14416
PDB IDs
4YYX
4XAQ
4XAS
5CNI
5CNJ
5KZN
5KZQ
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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