MED30 and MED27

Data Source:
BioGRID (biochemical)
HPRD (in vitro)

		MED30	MED27
Description		mediator complex subunit 30	mediator complex subunit 27
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Mediator Complex	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytosol Mediator Complex
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Nuclear Receptor Coactivator Activity Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Ubiquitin Protein Ligase Activity	Transcription Coactivator Activity Protein Binding
	Biological Process	Transcription Initiation From RNA Polymerase II Promoter Protein Ubiquitination Stem Cell Population Maintenance Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS		Common carotid intima-media thickness ( 29206233) Common carotid intima-media thickness in HIV infection ( 29206233) Dimensional psychopathology (Arousal) ( 29496196) Facial attractiveness (female raters) ( 30946739) Fasting blood glucose ( 29212154) Kawasaki disease ( 22446961) Leprosy ( 27976721) Midgestational total 25-hydroxyvitamin D levels (fetal genetic effect) ( 32047095) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Urate levels in obese individuals ( 25811787) Vestibular neuritis ( 30079052)	Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Gout (normal type) ( 32238385) Triglyceride levels ( 32203549)
Interacting Genes		17 interacting genes: APP DOCK8 HGS IFT20 KRTAP10-9 MED17 MED22 MED27 MED28 MED4 MED8 MED9 MTA2 NAP1L2 NME7 PCBD2 SS18L1	11 interacting genes: AFP ARFGAP1 ESR1 FBXO7 MED19 MED22 MED30 MED8 MED9 RBPJ SOX5
Entrez ID		90390	9442
HPRD ID		11631	05438
Ensembl ID		ENSG00000164758	ENSG00000160563
Uniprot IDs		Q96HR3	A0A024R8B7 Q6P2C8
PDB IDs
Enriched GO Terms of Interacting Partners?
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