SAPCD2 and GMNN

Data Source:
BioGRID (two hybrid)

		SAPCD2	GMNN
Description		suppressor APC domain containing 2	geminin DNA replication inhibitor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytosol Bicellular Tight Junction Apical Plasma Membrane Apical Junction Complex Apical Cortex	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Chromatin Binding Transcription Corepressor Activity Protein Binding Histone Deacetylase Binding Repressing Transcription Factor Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Positive Regulation Of Cell Population Proliferation Regulation Of Establishment Of Planar Polarity Symmetric Cell Division Negative Regulation Of Protein Localization To Cell Cortex	G1/S Transition Of Mitotic Cell Cycle Regulation Of DNA Replication Negative Regulation Of DNA Replication Animal Organ Morphogenesis Positive Regulation Of Chromatin Binding Negative Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated DNA Replication Preinitiation Complex Assembly Negative Regulation Of DNA-dependent DNA Replication
Pathways			CDT1 association with the CDC6:ORC:origin complex Activation of the pre-replicative complex
Drugs
Diseases
GWAS		Platelet count ( 32888494)	Metabolite levels ( 23823483)
Interacting Genes		13 interacting genes: ATF4 BFSP2 C1orf109 CYSRT1 EXOC7 GMNN GPRASP2 KRT3 KRTAP1-3 MDFI RALBP1 USHBP1 VCL	34 interacting genes: ARNT AURKA CASP3 CCDC146 CDKN1A CDKN2A CDT1 CSNK2A1 FZR1 GLIS2 HOXA10 HOXA11 HOXA7 HOXB7 HOXC8 HOXC9 HOXD10 IMPDH1 KANK2 KAT7 LNX1 MCM6 NCF1 PHC1 PTPN11 REPIN1 SAPCD2 SCMH1 SIX3 SMARCA4 UBE2C UBE2S ZNF250 ZNF439
Entrez ID		89958	51053
HPRD ID		12943	06783
Ensembl ID		ENSG00000186193	ENSG00000112312
Uniprot IDs		Q86UD0	A0A024QZY7 O75496
PDB IDs			1T6F 1UII 2LP0 2WVR 4BRY
Enriched GO Terms of Interacting Partners?
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