RHOT2 and ZFYVE9

Data Source:
HPRD (two hybrid)

		RHOT2	ZFYVE9
Description		ras homolog family member T2	zinc finger FYVE-type containing 9
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GO Annotations	Cellular Component	Mitochondrion Cytosol Plasma Membrane Membrane Integral Component Of Mitochondrial Outer Membrane	Early Endosome Cytosol Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle
	Molecular Function	GTPase Activity Calcium Ion Binding Protein Binding GTP Binding	Protein Binding 1-phosphatidylinositol Binding Protein Domain Specific Binding Metal Ion Binding
	Biological Process	Mitochondrion Organization Regulation Of Mitochondrion Organization Cellular Homeostasis Mitochondrion Transport Along Microtubule Regulation Of Small GTPase Mediated Signal Transduction Mitochondrial Outer Membrane Permeabilization	Endocytosis Transforming Growth Factor Beta Receptor Signaling Pathway Endosomal Transport
Pathways		Rho GTPase cycle
Drugs
Diseases
GWAS		Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Red blood cell traits ( 23446634)
Interacting Genes		5 interacting genes: PRKN SAR1A TMEM14B TMEM86B ZFYVE9	38 interacting genes: ANKLE2 BAG6 BMP4 CHD6 CLTC CTNNB1 DAZAP2 EIF4G1 ERBIN ETS2 FHL2 JUP LRP12 NIT1 NUP155 PML PPP1CA PPP1CB PPP1CC PPP2R1A RBBP6 RHOT2 RNF11 RNPEP SCYL2 SMAD2 SMAD3 SPART ST7 SUMF2 SUPT5H SVEP1 TENT5A TGFBR1 TGFBR2 UBC UBXN11 ZMYND8
Entrez ID		89941	9372
HPRD ID		15248	04782
Ensembl ID		ENSG00000140983	ENSG00000157077
Uniprot IDs		Q8IXI1	O95405
PDB IDs		5KUT	1DEV 1MK2 4BKW 5MJY
Enriched GO Terms of Interacting Partners?
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