ATP6V0E1 and TMEM254

Data Source:
BioGRID (two hybrid)

		ATP6V0E1	TMEM254
Description		ATPase H+ transporting V0 subunit e1	transmembrane protein 254
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain	Integral Component Of Membrane
	Molecular Function	Protein Binding Hydrolase Activity ATPase-coupled Ion Transmembrane Transporter Activity Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding
	Biological Process	Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS		Body mass index ( 27455349) PR interval ( 32439900)
Interacting Genes		19 interacting genes: - APOD ATP6V1E1 CDIPT COL8A2 CXCL16 EMP1 GPR25 KIR2DL3 MAL2 MS4A13 MS4A4A NAT8 OPRM1 PLN SYT15 TMEM218 TMEM254 YIPF6	41 interacting genes: AQP6 ARL13B ATP6V0E1 BCL2L13 BIK CD74 CD79A CERS4 CPLX4 EBP ELOVL4 FAM209A FKBP8 FNDC9 GPR152 GPX8 IFNGR2 IL3RA LEUTX LHFPL5 MFF MMGT1 MTIF3 PAGE1 PLP1 REEP4 RETREG3 SAR1A SEC11C SLC16A2 STOM STX1A SYT1 TMED8 TMEM14B TMEM237 TMEM31 TMEM45B TMEM51 TMEM79 TMX2
Entrez ID		8992	80195
HPRD ID		04894	08501
Ensembl ID		ENSG00000113732	ENSG00000133678
Uniprot IDs		O15342	A0A087WZM8 B4DU43 Q8TBM7
PDB IDs
Enriched GO Terms of Interacting Partners?
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