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CCNA1 and NPAT
Data Source:
BioGRID
(pull down)
CCNA1
NPAT
Description
cyclin A1
nuclear protein, coactivator of histone transcription
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cyclin-dependent Protein Kinase Holoenzyme Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Microtubule Cytoskeleton
Cyclin A1-CDK2 Complex
Cyclin A2-CDK2 Complex
Nucleus
Nucleoplasm
Cytoplasm
Cajal Body
Gemini Of Coiled Bodies
Molecular Function
Protein Binding
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
Transcription Coregulator Activity
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Binding
Protein C-terminus Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Male Meiosis I
Spermatogenesis
Protein Deubiquitination
Mitotic Cell Cycle Phase Transition
Cell Division
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
In Utero Embryonic Development
Regulation Of Gene Expression
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
G0 and Early G1
Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
Telomere Extension By Telomerase
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Regulation of APC/C activators between G1/S and early anaphase
SCF(Skp2)-mediated degradation of p27/p21
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
Ub-specific processing proteases
Processing of DNA double-strand break ends
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
Regulation of TP53 Activity through Phosphorylation
Regulation of TP53 Degradation
G2 Phase
Orc1 removal from chromatin
CDK-mediated phosphorylation and removal of Cdc6
G1/S-Specific Transcription
Cyclin A/B1/B2 associated events during G2/M transition
Cyclin A/B1/B2 associated events during G2/M transition
p53-Dependent G1 DNA Damage Response
Cyclin A:Cdk2-associated events at S phase entry
Drugs
Diseases
GWAS
Cocaine dependence (
31212010
)
Nickel levels (
26025379
)
Lymphocyte percentage of white cells (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Mosaic loss of chromosome Y (Y chromosome dosage) (
28346444
)
Nonunion in individuals with fractures (
30680360
)
Platelet count (
32888494
)
Plateletcrit (
27863252
)
Refractive error (
32231278
)
Interacting Genes
35 interacting genes:
ARID2
BRCA1
BRCA2
CABLES1
CDC20
CDC25A
CDK1
CDK2
CDKN1A
CDKN1B
CKS1B
CKS2
CUX1
E2F1
GPS2
H1-1
H1-5
H2BC1
INCA1
KLHDC9
MCM4
MCM6
MYBL2
NPAT
PGR
PROCA1
RACK1
RB1
RBL1
RBL2
RBM4
RPA1
SP1
SRC
XRCC6
3 interacting genes:
CCNA1
CREBBP
POU2F1
Entrez ID
8900
4863
HPRD ID
04946
03266
Ensembl ID
ENSG00000133101
ENSG00000149308
Uniprot IDs
A0A140VJG0
P78396
Q14207
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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