SYNJ2 and SYNJ2BP

Data Source:
HPRD (in vivo, in vitro)

		SYNJ2	SYNJ2BP
Description		synaptojanin 2	synaptojanin 2 binding protein
Image
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Cell Projection Membrane Raft Perinuclear Region Of Cytoplasm Presynapse	Mitochondrion Mitochondrial Outer Membrane Ionotropic Glutamate Receptor Complex Basolateral Plasma Membrane Cell Junction Neuromuscular Junction Neuron Projection Postsynaptic Density Membrane
	Molecular Function	RNA Binding Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Binding SH3 Domain Binding PDZ Domain Binding	Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Brain Development Inositol Phosphate Dephosphorylation Phosphatidylinositol Dephosphorylation Synaptic Vesicle Endocytosis Membrane Organization	Negative Regulation Of Endothelial Cell Proliferation Chemical Synaptic Transmission Regulation Of Notch Signaling Pathway Embryo Development Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Angiogenesis Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Negative Regulation Of ERK1 And ERK2 Cascade Receptor Localization To Synapse Cell-cell Adhesion Negative Regulation Of Sprouting Angiogenesis
Pathways		Synthesis of PIPs at the plasma membrane Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Cannabis use (initiation) ( 22823124) Gamma glutamyl transferase levels ( 29403010) Intraocular pressure ( 29617998) Lipoprotein (a) levels ( 26377243) Platelet distribution width ( 32888494)	Blood pressure ( 24954895) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) LDL cholesterol ( 30275531) Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes		6 interacting genes: GRB2 ITSN1 ITSN2 NCK1 RAC1 SYNJ2BP	33 interacting genes: ACTB ACVR2A ACVR2B APP AQP6 CD79A CPLX4 CREB3L1 CYB561 EBP ELOVL5 ELOVL7 ERGIC3 FAM210B FCER1G LHFPL5 LRP1 LRP2 LRP8 MEDAG RALBP1 REEP4 RPS6KA1 SLC10A6 SLC7A8 SYNJ2 THEM5 TLCD4 TMEM101 TMEM14B TMEM242 UBQLN1 USHBP1
Entrez ID		8871	55333
HPRD ID		10259	15455
Ensembl ID		ENSG00000078269	ENSG00000213463
Uniprot IDs		A0A1W2PR85 B4DG94 O15056	A0A024R670 P57105
PDB IDs		1UFW	2ENO 2JIK 2JIN
Enriched GO Terms of Interacting Partners?
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