SYNJ1 and FNBP4

Data Source:
HPRD (in vitro)

		SYNJ1	FNBP4
Description		synaptojanin 1	formin binding protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Microtubule Vesicle Membrane Membrane Coat Clathrin Coat Of Coated Pit Terminal Bouton Perinuclear Region Of Cytoplasm Synaptic Membrane Presynapse	Nuclear Speck
	Molecular Function	RNA Binding Phosphatidylinositol-3-phosphatase Activity Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity SH3 Domain Binding Phosphatidylinositol Phosphate 5-phosphatase Activity Phosphatidylinositol-4-phosphate Phosphatase Activity	Protein Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Neurotransmitter Transport Brain Development Learning Synaptic Vesicle Priming Synaptic Vesicle Uncoating Inositol Phosphate Metabolic Process Phosphatidylinositol Metabolic Process Inositol Phosphate Dephosphorylation Phosphatidylinositol Dephosphorylation Synaptic Vesicle Endocytosis Synaptic Vesicle Transport Membrane Organization Positive Regulation Of Endosome Organization
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of IP2, IP, and Ins in the cytosol Synthesis of IP3 and IP4 in the cytosol Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Platelet reactivity in response to clopidogrel treatment ( 32472697)	Alcohol use disorder (consumption score) ( 30336701) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Body mass index ( 28892062) Brain morphology (MOSTest) ( 32665545) Free thyroxine concentration ( 30367059) Fruit consumption ( 32066663) Global electrical heterogeneity phenotypes ( 29622589) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Medication use (antiglaucoma preparations and miotics) ( 31015401) Neuroticism ( 29255261) Refractive error ( 32231278) Sleep duration (short sleep) ( 30846698)
Interacting Genes		24 interacting genes: AMPH AP2A1 AP2M1 BIN1 CDK5 CLTA CLTC EPHB2 EPS15 FNBP4 GRB2 ITSN1 LRRK2 PACSIN1 PACSIN2 PACSIN3 PPP3CA SH3BP1 SH3GL1 SH3GL2 SH3GL3 SH3GLB1 SH3KBP1 SORBS2	10 interacting genes: CSNK2A1 FYN ITSN1 ITSN2 KHDRBS1 LBR PLXNA2 PRPF40A SNRPB SYNJ1
Entrez ID		8867	23360
HPRD ID		09182	10996
Ensembl ID		ENSG00000159082	ENSG00000109920
Uniprot IDs		A0A0D9SGJ6 B9EGN3 C9JFZ1 J3KQV8 O43426 Q05CZ1	Q8N3X1
PDB IDs		1W80 2DNR 2VJ0
Enriched GO Terms of Interacting Partners?
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