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TSC22D1 and GNB2
Data Source:
BioGRID
(two hybrid)
TSC22D1
GNB2
Description
TSC22 domain family member 1
G protein subunit beta 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Extracellular Space
Cytoplasm
Lysosomal Membrane
Cytosol
Heterotrimeric G-protein Complex
Plasma Membrane
Focal Adhesion
Membrane
Vesicle
Cell Body
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
Protein Binding
GTPase Activity
Calcium Channel Regulator Activity
Protein Binding
G-protein Gamma-subunit Binding
Protein-containing Complex Binding
GTPase Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Protein Folding
G Protein-coupled Receptor Signaling Pathway
Pathways
Activation of G protein gated Potassium channels
Glucagon signaling in metabolic regulation
G-protein activation
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
ADP signalling through P2Y purinoceptor 12
G beta:gamma signalling through PI3Kgamma
Prostacyclin signalling through prostacyclin receptor
Prostacyclin signalling through prostacyclin receptor
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
Ca2+ pathway
Ca2+ pathway
G alpha (q) signalling events
G alpha (12/13) signalling events
G beta:gamma signalling through PLC beta
G alpha (s) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
G alpha (i) signalling events
G alpha (z) signalling events
Glucagon-type ligand receptors
Thromboxane signalling through TP receptor
Vasopressin regulates renal water homeostasis via Aquaporins
Thrombin signalling through proteinase activated receptors (PARs)
Thrombin signalling through proteinase activated receptors (PARs)
Presynaptic function of Kainate receptors
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
G beta:gamma signalling through BTK
G beta:gamma signalling through CDC42
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs
Diseases
GWAS
Antineutrophil cytoplasmic antibody-associated vasculitis (
22808956
)
Body mass index (
25760438
)
Refractive error (
32231278
)
Rosacea symptom severity (
29771307
)
Hematocrit (
27863252
)
Hemoglobin concentration (
27863252
)
Hemoglobin levels (
32327693
)
Interacting Genes
50 interacting genes:
A2M
APLP1
ASAH1
CACNA1A
CARHSP1
CCDC90B
CHD3
CORO2B
CRMP1
DDAH2
DNMT3B
EED
ERG28
FAF1
FAM20C
FBN3
GNB2
GNB5
GORASP2
HMGXB4
KMT2B
KMT2C
LRIF1
MAP3K12
MCM3AP
NCOA5
NTAQ1
OTUB1
PDHB
PRKCI
PTN
QARS1
RGS1
RPL5
SETDB1
SP110
SPACA9
SPRED1
TAF5L
TGFBR1
TLE1
TP53
TSC22D4
UBE2D1
UNC119
VIM
WDR73
WIZ
WNK1
ZC3HC1
33 interacting genes:
ANXA7
ATXN10
CAPNS1
CDKN1A
CSNK1A1
FAM118B
FANCA
GADD45A
GNAI1
GNAI2
GNAI3
GNG10
GNG12
GNG13
GNG3
GNG4
GNG5
GNG7
GNGT1
GRB7
GRK2
GSK3B
ID3
MTNR1B
NR3C1
PCBP1
PDHB
RAF1
RASD2
RCC1
STAT5A
TGFBR1
TSC22D1
Entrez ID
8848
2783
HPRD ID
07414
11820
Ensembl ID
ENSG00000102804
ENSG00000172354
Uniprot IDs
A0A024RDV8
A0A087X0H8
A8K3Y6
Q15714
P62879
Q6FHM2
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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