LIN7A and MPP2

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		LIN7A	MPP2
Description		lin-7 homolog A, crumbs cell polarity complex component	membrane palmitoylated protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Bicellular Tight Junction Basolateral Plasma Membrane Synapse Extracellular Exosome MPP7-DLG1-LIN7 Complex Presynapse Postsynaptic Density Membrane	Cytoplasm Cytoskeleton Postsynaptic Density Dendrite Membrane Dendritic Spine Dendritic Shaft
	Molecular Function	Protein Binding L27 Domain Binding	Protein Binding
	Biological Process	Exocytosis Neurotransmitter Secretion Protein Transport Maintenance Of Epithelial Cell Apical/basal Polarity Synaptic Vesicle Transport Inner Ear Development Protein-containing Complex Assembly Protein Localization To Basolateral Plasma Membrane	Protein Homooligomerization Excitatory Postsynaptic Potential Long-term Synaptic Potentiation
Pathways		Dopamine Neurotransmitter Release Cycle Neurexins and neuroligins Assembly and cell surface presentation of NMDA receptors
Drugs
Diseases
GWAS		Age-related cataracts (age at onset) ( 25352737) Dental caries ( 23259602)	Cognitive function ( 24684796)
Interacting Genes		24 interacting genes: ABCA1 ADGRB1 APP BAIAP2 CASK CHRD DLG2 DLG3 DLG4 DNAJC5 ECM1 FAM9B GOLGA2 GRIN2B KCNJ12 MDFI MPP2 MPP3 MPP7 NOTCH2NLA PALS1 PALS2 SLC6A12 ZYX	7 interacting genes: CSNK2B DLG1 ERBIN LIN7A LIN7B LIN7C PLK1
Entrez ID		8825	4355
HPRD ID		04542	02837
Ensembl ID		ENSG00000111052	ENSG00000108852
Uniprot IDs		O14910	A0A0A0MRU0 A0A0C4DH75 B4DRL7 B4DZ84 D3DX48 D3DX49 Q14168
PDB IDs			2E7K
Enriched GO Terms of Interacting Partners?
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