RIPK1 and MAP3K8

  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

RIPK1

MAP3K8

Description receptor interacting serine/threonine kinase 1 mitogen-activated protein kinase kinase kinase 8
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cerebral white matter volume ( 31530798)
  • Depressive symptoms x independent stressful life events interaction (1df test) ( 30718454)
  • Depressive symptoms x independent stressful life events interaction (2df test) ( 30718454)
  • Idiopathic osteonecrosis of the femoral head ( 28000841)
Interacting Genes 45 interacting genes: BIRC3 CASP8 CCDC50 CDC42BPB CFLAR CRADD EGFR FADD FAS HSP90AA1 IKBKB IKBKE IKBKG ITCH MAP3K14 MAP3K3 MAP3K8 MTDH NFKB1 NUMBL OTUD1 PELI1 PTK2 RIPK3 RNF11 RNF216 SQSTM1 TAX1BP1 TBK1 TICAM1 TNF TNFAIP3 TNFRSF10A TNFRSF10B TNFRSF1A TRADD TRAF1 TRAF2 TRAF3 TRAF5 TRIM38 TRPC4AP UBE2N YOD1 ZFAND5 17 interacting genes: ACY3 AKT1 BMPR2 CD40 CHUK MAP2K1 MAP2K4 MAP3K14 NFKB1 NFKB2 REL RELA RIPK1 STIP1 TNIP2 TRAF2 TRAF6
Entrez ID 8737 1326
HPRD ID 04583 01863
Ensembl ID ENSG00000137275 ENSG00000107968
Uniprot IDs A0A024QZU0 Q13546 P41279 Q6FG25
PDB IDs 4ITH 4ITI 4ITJ 4NEU 5HX6 5TX5 5V7Z 6AC5 6C3E 6C4D 6HHO 6NW2 6NYH 6OCQ 6R5F 6RLN 4Y83 4Y85 5IU2
Enriched GO Terms of Interacting Partners?
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