HYAL2 and MST1R

Data Source:
HPRD (in vivo)

		HYAL2	MST1R
Description		hyaluronidase 2	macrophage stimulating 1 receptor
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosome Endoplasmic Reticulum Cytosol Plasma Membrane Microvillus Cell Surface Apical Plasma Membrane Endocytic Vesicle Anchored Component Of External Side Of Plasma Membrane Cytoplasmic Vesicle Membrane Raft Anchored Component Of Plasma Membrane Perinuclear Region Of Cytoplasm RNA Polymerase II Transcription Regulator Complex	Stress Fiber Vacuole Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Cell Surface Receptor Complex
	Molecular Function	Virus Receptor Activity Transcription Coactivator Activity Hyalurononglucosaminidase Activity Protein Binding Hyaluronic Acid Binding Enzyme Binding Receptor Signaling Protein Tyrosine Kinase Inhibitor Activity Receptor Tyrosine Kinase Binding Hyaluronoglucuronidase Activity Transforming Growth Factor Beta Binding	Transmembrane Receptor Protein Tyrosine Kinase Activity Macrophage Colony-stimulating Factor Receptor Activity Protein Binding ATP Binding Enzyme Binding
	Biological Process	Response To Reactive Oxygen Species Kidney Development Hematopoietic Progenitor Cell Differentiation Carbohydrate Metabolic Process Glycosaminoglycan Catabolic Process Response To Virus Multicellular Organism Aging Negative Regulation Of Fibroblast Migration Fusion Of Virus Membrane With Host Plasma Membrane Transformation Of Host Cell By Virus Hyaluronan Catabolic Process Negative Regulation Of Cell Growth Positive Regulation Of Interleukin-6 Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of Urine Volume Monocyte Activation Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of MAP Kinase Activity Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Transcription By RNA Polymerase II Response To Antibiotic Viral Entry Into Host Cell Skeletal System Morphogenesis Positive Regulation Of Inflammatory Response Cartilage Development Defense Response To Virus Negative Regulation Of Protein Kinase B Signaling Multicellular Organismal Iron Ion Homeostasis Negative Regulation Of Protein Tyrosine Kinase Activity Renal Water Absorption Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To UV-B Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Phagocytosis Defense Response Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Multicellular Organism Development Single Fertilization Nervous System Development Positive Regulation Of Cell Population Proliferation Response To Virus Cell Migration Peptidyl-tyrosine Phosphorylation Positive Regulation Of Kinase Activity Macrophage Colony-stimulating Factor Signaling Pathway Positive Regulation Of MAP Kinase Activity Innate Immune Response Hepatocyte Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Kinase B Signaling
Pathways		Hyaluronan uptake and degradation	Signaling by MST1
Drugs			Fostamatinib
Diseases
GWAS		Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Adult body size ( 32376654) Age at first birth ( 27798627) Body mass index ( 26426971 29273807) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Extremely high intelligence ( 29520040) Inflammatory bowel disease ( 23128233) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 25082827)
Interacting Genes		16 interacting genes: CYSRT1 FHL3 KRT31 KRT34 KRTAP1-1 KRTAP10-3 KRTAP3-2 KRTAP6-2 KRTAP6-3 MST1R PELI2 SMAD2 SMAD3 SMAD4 TRIM54 WWOX	24 interacting genes: AKT1 EPOR ERBB2 GAB1 GJB1 GRB2 HYAL2 JAK2 MST1 PIK3R1 PLCG1 PPP1CA PTPRR RELA SFN SHC1 SRC STUB1 YES1 YWHAB YWHAE YWHAH YWHAQ YWHAZ
Entrez ID		8692	4486
HPRD ID		04649	02545
Ensembl ID		ENSG00000068001	ENSG00000164078
Uniprot IDs		Q12891	B4E058 G9JXB8 Q04912
PDB IDs			3PLS 4FWW 4QT8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?