RFXANK and STOML2

Data Source:
BioGRID (enzymatic study)

		RFXANK	STOML2
Description		regulatory factor X associated ankyrin containing protein	stomatin like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Intercellular Bridge RNA Polymerase II Transcription Regulator Complex	Immunological Synapse Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytoskeleton COP9 Signalosome Actin Cytoskeleton Extrinsic Component Of Plasma Membrane T Cell Receptor Complex Membrane Raft
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Histone Deacetylase Binding	Signaling Receptor Binding Protein Binding GTPase Binding Cardiolipin Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Ras Protein Signal Transduction Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II	Mitochondrial Calcium Ion Transmembrane Transport Cellular Calcium Ion Homeostasis Mitochondrion Organization Lipid Localization Positive Regulation Of Mitochondrial Membrane Potential Interleukin-2 Production Mitochondrial Protein Processing CD4-positive, Alpha-beta T Cell Activation Mitochondrial ATP Synthesis Coupled Proton Transport T Cell Receptor Signaling Pathway Protein Complex Oligomerization Positive Regulation Of Mitochondrial DNA Replication Positive Regulation Of Cardiolipin Metabolic Process Stress-induced Mitochondrial Fusion
Pathways			Processing of SMDT1
Drugs
Diseases		Bare lymphocyte syndrome (BLS) type2 Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: CIITA HDAC4 HDAC5 RAF1 RFX5 RFXAP	4 interacting genes: APP GLP1R RABAC1 SUMO4
Entrez ID		8625	30968
HPRD ID		04435	16310
Ensembl ID		ENSG00000064490	ENSG00000165283
Uniprot IDs		A0A024R7M1 A0A024R7P0 O14593	A0A087WYB4 Q9UJZ1
PDB IDs		3UXG 3V30 6MEW
Enriched GO Terms of Interacting Partners?
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