ZFYVE19 and VPS4B

Data Source:
BioGRID (two hybrid, two hybrid, biochemical)

		ZFYVE19	VPS4B
Description		zinc finger FYVE-type containing 19	vacuolar protein sorting 4 homolog B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Midbody Cleavage Furrow Flemming Body	Spindle Pole Nucleus Cytoplasm Endosome Centrosome Cytosol Endosome Membrane Late Endosome Membrane Extracellular Exosome Flemming Body
	Molecular Function	Protein Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding	Protein Binding ATP Binding Protein C-terminus Binding Microtubule-severing ATPase Activity ATPase Activity Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding
	Biological Process	Abscission Negative Regulation Of Cytokinesis Mitotic Cytokinesis Checkpoint Cell Division	Potassium Ion Transport Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Viral Release From Host Cell Cholesterol Transport Cytoplasmic Microtubule Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Response To Lipid Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Viral Process Regulation Of Viral Process Microtubule Severing Protein Depolymerization Negative Regulation Of Cell Death Late Endosomal Microautophagy Midbody Abscission Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion Positive Regulation Of Centriole Elongation Positive Regulation Of Viral Life Cycle ESCRT III Complex Disassembly
Pathways			Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Anxiety and stress-related disorders ( 31116379) Malaria ( 31844061)	Pyoderma gangrenosum in inflammatory bowel disease ( 24487271)
Interacting Genes		10 interacting genes: AXIN1 CAPN7 CCHCR1 DPY30 HTT MITD1 TRIM55 TRIM63 VPS4B ZDHHC17	8 interacting genes: CHMP1A CHMP1B CHMP2A CHMP5 HTRA2 KATNAL1 VPS4A ZFYVE19
Entrez ID		84936	9525
HPRD ID		15731	15653
Ensembl ID		ENSG00000166140	ENSG00000119541
Uniprot IDs		Q96K21	A0A024R2C5 O75351
PDB IDs			1WR0 1XWI 2CPT 2JQH 2JQK 4U7Y
Enriched GO Terms of Interacting Partners?
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