ZNF566 and KIF2C

Data Source:
BioGRID (two hybrid)

		ZNF566	KIF2C
Description		zinc finger protein 566	kinesin family member 2C
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Nucleus Centrosome Spindle Cytosol Kinesin Complex Microtubule Cytoplasmic Microtubule Microtubule Cytoskeleton Membrane Microtubule Plus-end
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity Centromeric DNA Binding Microtubule Plus-end Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Microtubule Depolymerization Mitotic Metaphase Plate Congression Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Cell Division Metaphase Plate Congression Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Chromosome Segregation
Pathways		Generic Transcription Pathway	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins
Drugs			Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS
Interacting Genes		6 interacting genes: EXOC8 KIF2C KIF9 MAGOHB TRIM55 TRIM63	10 interacting genes: APP AURKA CENPH CSNK2B H3-4 NDEL1 PLK1 SUMO2 VHL ZNF566
Entrez ID		84924	11004
HPRD ID		15847	05172
Ensembl ID		ENSG00000186017	ENSG00000142945
Uniprot IDs		B4DRR6 Q969W8	A0A140VKF1 B7Z6Q6 B7Z7M6 Q99661
PDB IDs			2HEH 4UBF 4Y05 5MIO
Enriched GO Terms of Interacting Partners?
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