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RIOX2 and H3C3
Data Source:
BioGRID
(enzymatic study)
RIOX2
H3C3
Description
ribosomal oxygenase 2
H3 clustered histone 3
Image
GO Annotations
Cellular Component
Nucleoplasm
Transcription Regulator Complex
Nucleolus
Cytosol
Nuclear Chromosome
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Membrane
Protein-containing Complex
Extracellular Exosome
Molecular Function
Transcription Corepressor Activity
Protein Binding
2-oxoglutarate-dependent Dioxygenase Activity
Histone Demethylase Activity (H3-K4 Specific)
Identical Protein Binding
Metal Ion Binding
Histone Demethylase Activity (H3-K36 Specific)
DNA Binding
Protein Binding
Cadherin Binding
Protein Heterodimerization Activity
Biological Process
Histone H3-K4 Demethylation
Ribosome Biogenesis
Negative Regulation Of Transcription, DNA-templated
Histone H3-K36 Demethylation
RDNA Heterochromatin Assembly
Chromatin Organization
Nucleosome Assembly
DNA Replication-dependent Nucleosome Assembly
Blood Coagulation
Telomere Organization
Interleukin-7-mediated Signaling Pathway
Cellular Protein Metabolic Process
Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Gene Silencing By MiRNA
Regulation Of Gene Silencing
Pathways
HDMs demethylate histones
Interleukin-7 signaling
Interleukin-7 signaling
Pre-NOTCH Transcription and Translation
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
HDACs deacetylate histones
PKMTs methylate histone lysines
HDMs demethylate histones
HATs acetylate histones
HATs acetylate histones
RMTs methylate histone arginines
Chromatin modifying enzymes
SIRT1 negatively regulates rRNA expression
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
NoRC negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
DNA methylation
Transcriptional regulation by small RNAs
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
RNA Polymerase I Promoter Opening
RNA Polymerase I Promoter Escape
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Estrogen-dependent gene expression
Meiotic recombination
HCMV Early Events
HCMV Late Events
Transcriptional regulation of granulopoiesis
Amyloid fiber formation
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Interacting Genes
4 interacting genes:
APP
H3C3
LNX1
MYC
10 interacting genes:
ASF1A
ASF1B
CBX1
CENPA
DAXX
DNAJC9
NASP
PHF1
RIOX2
TRIM24
Entrez ID
84864
8352
HPRD ID
17575
11906
Ensembl ID
ENSG00000170854
ENSG00000287080
Uniprot IDs
A0A6M8YDW1
Q8IUF8
P68431
PDB IDs
2XDV
4BU2
4BXF
1CS9
1CT6
1O9S
1Q3L
2B2T
2B2U
2B2V
2B2W
2C1J
2C1N
2CO0
2CV5
2FSA
2KWJ
2KWK
2L75
2LBM
2LGG
2M0O
2NDF
2NDG
2OQ6
2OT7
2OX0
2RI7
2RR4
2UXN
2V85
2V89
2VNF
2VPG
2X0L
3A1B
3AFA
3AVR
3AYW
3AZE
3AZF
3AZG
3AZH
3AZI
3AZJ
3AZK
3AZL
3AZM
3AZN
3B95
3FDT
3KMT
3KQI
3LQI
3LQJ
3MP1
3O34
3O35
3O37
3QJ6
3RIG
3RIY
3SOU
3SOW
3U31
3U3D
3U4S
3U5N
3U5O
3U5P
3UEE
3UEF
3UIG
3UII
3UIK
3V43
3W96
3W97
3W98
3W99
3WA9
3WAA
3WKJ
3X1S
3X1T
3X1U
3X1V
3ZG6
3ZVY
4A0J
4A0N
4A7J
4BD3
4C1Q
4F4U
4F56
4FWF
4HON
4I51
4L7X
4LK9
4LKA
4LLB
4LXL
4N4H
4QBQ
4QBR
4QBS
4TN7
4U68
4UP0
4UY4
4X3K
4Y6L
4YHP
4YHZ
4YM5
4YM6
4Z0R
4Z2M
5AV5
5AV6
5AV8
5AV9
5AVB
5AVC
5B24
5B2I
5B2J
5B31
5C11
5C13
5C3I
5CPI
5CPJ
5CPK
5D6Y
5DAH
5FB0
5FB1
5FFV
5GH9
5GSE
5GSU
5GT0
5GT3
5GTC
5H6Q
5H6R
5HJB
5HJC
5HJD
5HYN
5IQL
5J3V
5J9S
5JHN
5JIN
5JIY
5JJ0
5JRG
5KJH
5KJI
5KKL
5LUG
5M5G
5MR8
5NNC
5NND
5OY3
5SVX
5SVY
5SZB
5SZC
5T0K
5T0M
5T1G
5T1I
5T8R
5TBN
5TDR
5TDW
5U2J
5V21
5V22
5VA6
5VAB
5VGE
5VNB
5WFC
5WLE
5WVO
5WXG
5WXH
5WYI
5X60
5XF3
5XF4
5XF5
5XFQ
5XFR
5XNV
5XTZ
5Y0C
5Y0D
5Y20
5Y2F
5Z23
5Z30
6AXJ
6AZE
6BHD
6BHE
6BHG
6BHH
6BHI
6D07
6D08
6E83
6E86
6F6D
6HKT
6HTS
6IEU
6IIS
6IIT
6IPU
6IQ4
6JOU
6JR0
6JR1
6JXD
6K1I
6K1J
6K1K
6KE9
6KVD
6L49
6L4A
6L9H
6LA8
6LA9
6LE9
6M3V
6M44
6M4D
6M4G
6M4H
6MIL
6MIM
6MIN
6MIO
6MIQ
6R8Y
6R8Z
6R90
6R91
6R92
6R93
6R94
6T90
6T93
6UPK
6UPL
6USJ
6V2H
6V3N
6V41
6V92
6VIL
6WAV
6WW4
6YIF
6YIH
6YOV
7C0M
7CCQ
7CCR
Enriched GO Terms of Interacting Partners
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