GTPBP3 and PARP11

Data Source:
HPRD (two hybrid)

		GTPBP3	PARP11
Description		GTP binding protein 3, mitochondrial	poly(ADP-ribose) polymerase family member 11
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion	Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Nuclear Body
	Molecular Function	GTPase Activity Protein Binding GTP Binding	NAD+ ADP-ribosyltransferase Activity Protein ADP-ribosylase Activity
	Biological Process	TRNA Wobble Uridine Modification TRNA Methylation	Nuclear Envelope Organization Spermatogenesis Protein Transport Cell Differentiation MRNA Transport Protein Auto-ADP-ribosylation Protein Mono-ADP-ribosylation
Pathways		tRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Mitochondrial DNA copy number ( 30704525)	Cognitive performance ( 20125193) Colorectal cancer ( 23263487) Emotional lability in attention deficit hyperactivity disorder ( 31085060) Fasting insulin (dietary factor interaction) ( 24204828) Hematocrit ( 29403010) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 29403010 32888494) Pulse pressure ( 27841878) Red blood cell count ( 29403010) Total hippocampal volume ( 30279459) White coat effect (clinic diastolic blood pressure minus ambulatory diastolic blood pressure) ( 31044621)
Interacting Genes		28 interacting genes: BEND7 CAPN3 CCDC32 CIC COPS5 DCAF8 DPPA4 GNE INCA1 ITGB3BP MBD3L1 MEOX2 MESD PARP11 PFKL POLDIP3 PPP1R18 PRPF3 PTAFR RALY RIBC2 SERTAD3 SINHCAF TBC1D3B TBC1D3G ZFP90 ZNF69 ZNF774	7 interacting genes: DTX3 GTPBP3 HOOK2 LHX3 LHX4 MDFI TRIP13
Entrez ID		84705	57097
HPRD ID		12255	15101
Ensembl ID		ENSG00000130299	ENSG00000111224
Uniprot IDs		B7Z563 Q969Y2	Q9NR21
PDB IDs			2DK6
Enriched GO Terms of Interacting Partners?
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