FKBP6 and GSC2

Data Source:
BioGRID (two hybrid)

		FKBP6	GSC2
Description		FKBP prolyl isomerase family member 6 (inactive)	goosecoid homeobox 2
Image			No pdb structure
GO Annotations	Cellular Component	Synaptonemal Complex Cytoplasm Cytosol	Chromatin Nucleus
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Identical Protein Binding Hsp90 Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization Protein Folding Spermatogenesis Cell Differentiation Gene Silencing By RNA PiRNA Metabolic Process DNA Methylation Involved In Gamete Generation Positive Regulation Of Viral Genome Replication Meiotic Cell Cycle	Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis
Pathways		Meiotic synapsis PIWI-interacting RNA (piRNA) biogenesis
Drugs
Diseases
GWAS		Height ( 31562340) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)	Metabolite levels ( 22916037)
Interacting Genes		37 interacting genes: ACD ALDH3A1 CCDC198 CCNK CDK5RAP3 CFP CRACR2A DDIT4L DLGAP4 ECM1 EEF1D ENKD1 FAM107A GAPDH GSC2 HSP90AA1 IHO1 KANK2 KRT75 LZTS2 MAP3K1 MEI4 MEOX2 NME7 NTAQ1 PIAS2 PICK1 PPP1R32 RAB11FIP2 RNF4 SUMO1P1 TEPSIN TINF2 TMEM9B TRIM55 TRIM63 ZNF655	60 interacting genes: ALPP ANXA5 ASPH BEST3 BNIP2 C19orf47 C1D CALM1 CALM2 CALM3 CALR CDKN2D CIAO2A COL8A1 CRCP CSNK2A1 DYRK1B EGLN3 EIF5A ETFDH FAM221B FKBP6 GALNT11 GCM2 GTF2H5 GTSF1L GUCA1A GUCY1A2 HMBOX1 ISX KDM6A KLHL38 KRT34 KRTAP5-9 LCE3E LTO1 MAD2L2 MAPK9 MARF1 MID2 MORF4L1 MRPL53 MRPS23 NME7 PACSIN2 PDE4C PRKAB2 PTER RNF4 SCAF1 SDCBP TIPIN TNPO2 TSR2 UBE2R2 VCX2 XRCC4 YPEL5 ZNF444 ZNF587
Entrez ID		8468	2928
HPRD ID		05326	03506
Ensembl ID		ENSG00000077800	ENSG00000063515
Uniprot IDs		A0A3B3IST2 O75344	O15499
PDB IDs		3B7X
Enriched GO Terms of Interacting Partners?
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