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TRIM63 and EED
Data Source:
BioGRID
(two hybrid)
TRIM63
EED
Description
tripartite motif containing 63
embryonic ectoderm development
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Microtubule
Z Disc
M Band
Nucleus
Nucleoplasm
Chromosome
Cytosol
ESC/E(Z) Complex
Molecular Function
Protein Binding
Zinc Ion Binding
Titin Binding
Ubiquitin Protein Ligase Activity
RNA Polymerase II Transcription Corepressor Binding
Protein Binding
Nucleosome Binding
Histone Methyltransferase Activity
Identical Protein Binding
Histone Methyltransferase Activity (H3-K27 Specific)
Biological Process
Muscle Contraction
Signal Transduction
Negative Regulation Of Cardiac Muscle Hypertrophy
Skeletal Muscle Atrophy
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Protein Ubiquitination
Response To Glucocorticoid
Response To Interleukin-1
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Silencing
Viral Process
Negative Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of G0 To G1 Transition
Histone H3-K27 Methylation
Pathways
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Antigen processing: Ubiquitination & Proteasome degradation
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
PKMTs methylate histone lysines
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
HCMV Early Events
Drugs
Diseases
GWAS
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Refractive error (
32231278
)
Smoking initiation (ever regular vs never regular) (
30679032
)
Smoking status (ever vs never smokers) (
30643258
)
Interacting Genes
329 interacting genes:
ACBD4
ACD
ACTA1
ADAMTSL4
AEBP2
AGO2
AK1
AKR7A2
ALDOA
ALKBH3
ANKRD1
ANKRD39
APLN
APOBEC4
APP
ARL6IP4
ATP5F1B
ATP5F1D
ATXN3
ATXN3L
ATXN7L1
BAP1
BCAT1
BCHE
BRD4
BRWD1
BTBD9
C10orf88
C12orf4
C1orf35
C3orf36
C8orf74
CADPS
CAMK2A
CAPN3
CARS1
CBX2
CCDC120
CCDC130
CCDC28B
CDK3
CDS2
CENPK
CHMP7
CKB
CKM
COA7
COX4I1
CRCT1
CTAG1A
CTAG1B
CTNNB1
CYB5R2
CYP46A1
CYTOR
DAPL1
DCAF11
DCAF6
DECR2
DEF8
DEK
DES
DNTTIP1
DOCK7
DYNLT2B
EED
EEF1G
EHHADH
EIF3E
ELAPOR1
ENO3
EPS8L2
ESPL1
EZH2
FAM185A
FANK1
FASTKD1
FHL2
FKBP6
FLNC
FRMD6
FYN
GABPB1
GATA3
GFM1
GLI4
GMEB1
GOLGA2P5
GPRIN2
GPS1
GRB10
HIBADH
HID1
HIRA
HOXA1
HROB
HSPB1
HSPD1
ID1
IFI35
IGF2
IK
IL37
ILF3
INCA1
ING4
INKA1
IQUB
IRF2
IRF3
ITGB5
JADE3
JOSD1
KBTBD4
KCTD15
KIAA0087
KIAA0408
KIAA0825
KIF5A
KLHDC4
KLHL36
KMT2B
KYAT1
LAMA2
LAMTOR5
LAPTM4A
LIMS2
LINC00518
LINC00663
LINC00905
LINC01588
LMCD1
LMO2
LRRC56
LYN
LYNX1
MAGEC3
MALSU1
MAP3K14
MBD4
MBIP
MCM7
MIDN
MIIP
MKI67
MLH3
MPP1
MPZL1
MRPL19
MRPL20-AS1
MRPL41
MSRB3
MYBPC1
MYBPC2
MYBPC3
MYBPHL
MYC
MYCT1
MYH6
MYL2
MYOT
MYOZ1
NDUFA1
NDUFA8
NEB
NEBL
NEFL
NGEF
NOMO1
NR1D2
NRAP
NSD3
NSUN7
NUFIP2
ODF2
OGFOD2
OTUB1
OTUB2
P3H3
PACRGL
PAFAH1B2
PCGF3
PCGF6
PDHB
PDK4
PELI3
PELO
PHC2
PHF23
PIAS1
PIAS2
PIAS3
PIP4K2B
PKM
PLEKHG4
PLXNA3
POLR2E
PPA2
PPARA
PPIE
PRKAB2
PRKACA
PRR30
PRRT1
PSMD4
PYGM
RAI2
RBM14
RELA
REX1BD
RGR
RHEB
RHPN1
RING1
RNASEH1
RNF10
RPS4X
RRAS
RUSC1
RUSC1-AS1
SEC23B
SENP2
SENP3
SET
SGCB
SHFL
SLC6A13
SLFN12
SNAPIN
SNW1
SPATS1
SPRYD7
SPSB1
SPSB2
SQSTM1
SRF
STAM
SUMO2
SYMPK
SYNCRIP
TCAP
TCEAL4
TCP10L
TEX19
THAP3
THRA
TIGD5
TIMM17B
TMBIM1
TMEM35A
TNIP3
TNNC1
TNNI1
TNNI2
TNNI3
TNNT1
TNNT3
TOR1AIP2
TPD52L3
TRAF3IP2
TRIB3
TRIM23
TRIM35
TRIM41
TRIM54
TRIM55
TRIM69
TRMT10B
TSC2
TSC22D4
TTN
TUBGCP4
UBA3
UBE2D1
UBE2D2
UBE2D3
UBE2E3
UBE2I
UBE2J1
UBE2K
UBE2N
UBE2U
UBE2V2
UCHL1
UCHL3
UCHL5
UNKL
UQCRC1
USP13
USP15
USP2
USP21
USP28
USP33
USP4
USP5
USP7
USP8
UXT
VAC14
VPS37A
WT1
XAGE1B
YOD1
YPEL3
ZBTB17
ZC2HC1C
ZC3H12A
ZC3HC1
ZFYVE19
ZNF124
ZNF20
ZNF302
ZNF333
ZNF345
ZNF431
ZNF436
ZNF460
ZNF566
ZNF57
ZNF581
ZNF597
ZNF649
ZNF653
ZNF667-AS1
ZNF767P
ZNF775
ZNF83
ZSCAN16
42 interacting genes:
AEBP2
ANXA5
AR
BRCA1
CDK2AP2
CTSL
DNMT1
DNMT3A
DNMT3B
DUSP23
EHMT1
EPC2
EZH1
EZH2
FHL1
H1-1
H3C1
HDAC1
HDAC2
HDAC3
ITGA4
ITGAE
ITGB7
MAP1LC3B
NUDT21
PJA1
PPP1CA
PPP1R8
PRDM14
RACK1
RPS10
SELENBP1
SMYD3
SRPK2
TGS1
TRIM55
TRIM63
TSC22D1
UBE2W
YY1
ZBED8
ZFP42
Entrez ID
84676
8726
HPRD ID
05843
09343
Ensembl ID
ENSG00000158022
ENSG00000074266
Uniprot IDs
Q969Q1
E9PJK2
O75530
PDB IDs
2D8U
3DDT
4M3L
3IIW
3IIY
3IJ0
3IJ1
3IJC
3JPX
3JZG
3JZH
3JZN
3K26
3K27
4W2R
4X3E
5GSA
5H13
5H14
5H15
5H17
5H19
5H24
5H25
5HYN
5IJ7
5IJ8
5K0M
5LS6
5TTW
5U5H
5U5K
5U5T
5U62
5U69
5U6D
5U8A
5U8F
5WG6
5WP3
5WUK
6B3W
6C23
6C24
6SFB
6SFC
6U4Y
6W7F
6W7G
Enriched GO Terms of Interacting Partners
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